Results 101 to 110 of about 573,045 (266)

Primary producers' positions towards bears and bear conservation: Insights for human–bear coexistence

open access: yesPeople and Nature
We present primary producers' (farmers', livestock breeders', beekeepers') positions towards bears and bear conservation as documented through semi‐structured interviews within the frame of human dimensions actions of LIFE projects implemented between ...
Tasos Hovardas   +2 more
doaj   +1 more source

Big Bear billboard near Main street

open access: yes, 1930
A long and narrow billboard, near the 2030 East Main Street store, helping to introduce Big Bear's second supermarket. The billboard reads, "Big Bear: The one complete, one stop stop super food market.
Big Bear
core  

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

open access: yesFEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson   +2 more
wiley   +1 more source

Multi-Temperature Crystallography of S-Adenosylmethionine Decarboxylase Observes Dynamic Loop Motions

open access: yesBiomolecules
S-adenosylmethionine decarboxylase (AdoMetDC) is an essential enzyme in the polyamine biosynthesis pathway and plays a key role in the synthesis of the polyamines spermidine and spermine, polycationic alkylamines that are present in millimolar levels in ...
Jenitha R. Patel   +4 more
doaj   +1 more source

Wayne E. Brown on horseback at Big Bear Farms

open access: yes, 1962
Black and white photograph of Big Bear stores President, Wayne E. Brown, at Big Bear Farms in Powell, Ohio. In 1934, an innovation in food retailing was introduced in Columbus when Wayne E. Brown opened the first self-service supermarket in central Ohio.
Big Bear
core  

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

open access: yesFEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan   +2 more
wiley   +1 more source

Effect of thermal history on the fracture and fatigue behaviors of semi-crystalline polymers prepared via material extrusion additive manufacturing

open access: yesMaterials & Design
Material extrusion (MEX) additive manufacturing (AM) is transforming the design and production of complex structures, providing reliable on-demand components.
Ava M. Lea   +3 more
doaj   +1 more source

Produce at the Lancaster Big Bear location

open access: yes, 1940
Produce department at the Lancaster, Ohio Big Bear location. Big Bear is responsible for many innovations in the supermarket business. They were the first to introduce motorized counters that were controlled by the cashier.
Big Bear
core  

Cell surface CD11c as a neutrophil aging marker molecule

open access: yesFEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki   +5 more
wiley   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

open access: yesFEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

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