Results 81 to 90 of about 475,810 (306)

Using tri-axial accelerometers to identify wild polar bear behaviors

open access: yes, 2017
Tri-axial accelerometers have been used to remotely identify the behaviors of a wide range of taxa. Assigning behaviors to accelerometer data often involves the use of captive animals or surrogate species, as their accelerometer signatures are generally ...
A. Pagano   +12 more
semanticscholar   +1 more source

Drivers of hibernation in the brown bear

open access: yesFrontiers in Zoology, 2016
Hibernation has been a key area of research for several decades, essentially in small mammals in the laboratory, yet we know very little about what triggers or ends it in the wild.
Alina L. Evans   +9 more
semanticscholar   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Recent Hybridization between a Polar Bear and Grizzly Bears in the Canadian Arctic

open access: yes, 2017
Grizzly bears have recently become more common on the Arctic Islands in the Inuvialuit Settlement Region, concurrently with a period of environmental change.
Jodie D. Pongracz   +3 more
semanticscholar   +1 more source

Substitutes for Bear Bile for the Treatment of Liver Diseases: Research Progress and Future Perspective

open access: yesEvidence-Based Complementary and Alternative Medicine, 2016
Bear bile has been a well-known Chinese medicine for thousands of years. Because of the endangered species protection, the concept on substitutes for bear bile was proposed decades ago.
Sha Li   +6 more
semanticscholar   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Zanesville Big Bear store

open access: yes, 1948
Black and white photograph of the exterior of the Zanesville Big Bear location, in June of 1948. Big Bear is responsible for many innovations in the supermarket business.
Big Bear
core  

Retreat and extinction of the Late Pleistocene cave bear (Ursus spelaeus sensu lato)

open access: yesSCIENCE NATURE, 2016
The cave bear (Ursus spelaeus sensu lato) is a typical representative of Pleistocene megafauna which became extinct at the end of the Last Glacial. Detailed knowledge of cave bear extinction could explain this spectacular ecological transformation.
M. Baca   +6 more
semanticscholar   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Big Bear bakey photo

open access: yes, 1962
Black and white photo of a Big Bear bakery, featured in the Grocers Beacon, Special Edition on Big Bear. Big Bear Bakeries, Inc. ("Bakery") owned and operated a central bakery in Columbus and manufactured and distributed fresh bread and pastery products ...
Big Bear
core  

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