Results 41 to 50 of about 23,126 (247)

When the State Imposes the “Commons”: Pastoralism After the Reintroduction of the Brown Bear in the Pyrenees

open access: yesConservation & Society, 2021
After the brown bear reintroduction program was launched in the Pyrenees in 1996, the French and Spanish States fostered and funded a regrouping policy to protect the sheep flocks from the bear attacks.
Ferran Pons-Raga   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Là où s’échouent les destinées. Les prisons, dévoreuses de mémoires ?

open access: yesBulletin de l’Association de Géographes Français, 2021
Confronted with prison confinement, prisoners are faced with several difficulties (family, social, financial, professional, judicial, administrative, etc.). If for the academic world these factors of vulnerability are obvious, another phenomenon needs to
Thibault Ducloux
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Brown bear (Ursus arctos) attacks resulting in human casualties in Scandinavia 1977-2016; management implications and recommendations.

open access: yesPLoS ONE, 2018
Human persecution and habitat loss have endangered large carnivore populations worldwide, but some are recovering, exacerbating old conflicts. Carnivores can injure and kill people; the most dramatic form of wildlife-human conflict.
Ole-Gunnar Støen   +9 more
doaj   +1 more source

Ethnozoology as an applied approach for biodiversity conservation in Hyrcanian forests [PDF]

open access: yesDānishhā-yi būmī-i Īrān
The historical relationship between humans and nature can be introduced and investigated with Indigenous ecological knowledge used in conservation policy-making and should be considered in governmental and formal conservation.
Elmira Sharbafi   +4 more
doaj   +1 more source

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