Results 91 to 100 of about 994,111 (289)

Environmental and Mineralogical Characteristics of Tourmaline-bearing localities in the United States

, 2020
J. Williams
openalex   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Intelligent Design Method for Thermal Conductivity Topology Based on a Deep Generative Network

Chinese Journal of Mechanical Engineering
Heat dissipation performance is critical to the design of high-end equipment, such as integrated chips and high-precision machine tools. Owing to the advantages of artificial intelligence in solving complex tasks involving a large number of variables ...
Qiyin Lin, Feiyu Gu, Chen Wang, Hao Guan, Tao Wang, Kaiyi Zhou, Lian Liu, Desheng Yao   +7 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

POST-CRITICAL DEFORMATION OF THIN-WALLED LOAD-BEARING AIRCRAFT STRUCTURE REPRESENTING FRAGMENT OF THE ONE-WAY TORSION BOX [PDF]

, 2018
Tomasz Kopecki, Tomasz Lis, Przemysław Mazurek   +2 more
openalex   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Simplified 2D Finite Element Model for Calculation of the Bearing Capacity of Eccentrically Compressed Concrete-Filled Steel Tubular Columns [PDF]

, 2021
Антон Чепурненко, Batyr Yazyev, Besarion Meskhi, Alexey N. Beskopylny, Kazbek Khashkhozhev, Viacheslav Chepurnenko   +5 more
openalex   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Low-temperature tribological properties of Si3N4 ceramic composites incorporating nano/microscale graphene and Si3N4 whisker

Journal of Materials Research and Technology
Si3N4 ceramic bearings have demonstrated significant potential in augmenting the performance of liquid rockets. However, the operational conditions, including reciprocating use, ultra-high-speeds, and high-load impacts, impose more stringent requirements
Fei Chen, Xiaobo Sun, Bin Fang, Ke Yan, Bei Yan   +4 more
doaj   +1 more source

Electrophysiological assessment of water stress in fruit-bearing woody plants

, 2014
Liliana Ríos Rojas, Franco Tapia, Luis Gurovich   +2 more
openalex   +1 more source