Results 71 to 80 of about 1,478,908 (297)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Bearing defect diagnosis and acoustic emission. [PDF]

open access: yes, 2003
Acoustic emission (AE) was originally developed for non-destructive testing of static structures, however, over the years its application has been extended to health monitoring of rotating machines and bearings.
Mba, David   +3 more
core   +1 more source

The Impact of Surface Roughness on the Friction and Wear Performance of GCr15 Bearing Steel

open access: yesLubricants
Surface roughness plays a crucial role in determining surface quality, influencing factors such as vibration, noise, assembly precision, lubrication, and wear resistance in bearings.
Tiantian He   +5 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Detection method for contact stress distribution of tapered roller bearings

open access: yesScientific Reports
The axle box of high-speed train adopts double row tapered roller bearings as transmission parts, and the reliability of bearings directly affects the safety of train operation.
Ye Ji   +5 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Running performance of an aerodynamic journal bearing with squeeze film effect [PDF]

open access: yes, 2013
Results of theoretical and experimental studies concerning the performance of an aerodynamic journal bearing which running is assisted by squeeze film ultrasonic levitation (SFUL) are presented in this paper.
Stolarski, TA, Sho, T, Yoshimoto, S
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Influence of operational variables in a hydrodynamic bearing on the generation of acoustic emission [PDF]

open access: yes, 2010
Detecting mechanical faults of rotating machines particularly in hydrodynamic bearings has been recognised as important for preventing sudden shut downs.
Mba, David   +5 more
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

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