Results 91 to 100 of about 1,478,908 (297)

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Non-linearity in experimental journal bearing dynamics - a new approach [PDF]

, 2009
This article considers the effects of non-linearity in the dynamic properties of a journal bearing and presents a method of constructing the calculations needed in the identification of a non-linear dynamic model of the oil film.
Mba, David, Wale, G. D.
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Validation of a finite-element model of a 5 m three-row roller wind turbine blade bearing [PDF]

Wind Energy Science
Large rolling bearings with complex interfaces need reliable finite-element (FE) models to determine the load distribution and deformation behavior. To ensure the accuracy of the results, it is important to validate the models against experimental data ...
M. Graßmann, M. Geibel, F. Schleich
doaj   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

A Study of Motor Bearing Fault Diagnosis using Modulation Signal Bispectrum Analysis of Motor Current Signals [PDF]

, 2013
Failure of induction motors are a large concern due to its influence over industrial production. Motor current signature analysis (MCSA) is common practice in industry to find motor faults. This paper presents a new approach to detection and diagnosis of
Chen, Zhi, Gu, Fengshou, Ball, Andrew, Alwodai, Ahmed, Wang, Tie, Cattley, Robert   +5 more
core   +1 more source

Fault Feature Extraction and Diagnosis of Rolling Bearings Based on Enhanced Complementary Empirical Mode Decomposition with Adaptive Noise and Statistical Time-Domain Features

Sensors, 2019
In this paper, a novel method is proposed to enhance the accuracy of fault diagnosis for rolling bearings. First, an enhanced complementary empirical mode decomposition with adaptive noise (ECEEMDAN) method is proposed by determining two critical ...
Liwei Zhan, Fang Ma, Jingjing Zhang, Chengwei Li, Zhenghui Li, Tingjian Wang   +5 more
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Effect of laser shock peening on microstructural evolution and tribological performance of Cronidur30 high-nitrogen bearing steel

Journal of Materials Research and Technology
Improving the tribological performance of bearing steels by laser shock peening (LSP) remains challenging because the beneficial effects of near-surface strengthening must be balanced against the accompanying changes in surface topography, particularly ...
Yang Cao, Tiantian He, Wenbo Chen, Zeyuan Liu, Jiale Chen, Sanming Du, Yongzhen Zhang   +6 more
doaj   +1 more source