Results 141 to 150 of about 3,237,410 (336)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Recent progress in high-temperature greases: Constitutive relationships, mechanisms, and applications

open access: yesFriction
In modern high-tech industries, such as aerospace, nuclear energy, and electric power, there is increasing demand for materials with high-temperature adaptability and superior lubrication properties.
Haolin Li   +5 more
doaj   +1 more source

Evaluation of a hybrid hydrostatic bearing for cryogenic turbopump application [PDF]

open access: yes
A hybrid hydrostatic bearing was designed to operate in liquid hydrogen at speeds to 80,000 rpm and radial loads to 440 n (100 lbf). The bearing assembly consisted of a pair of 20-mm angular-contact ball bearings encased in a journal, which was in turn ...
Hannum, N. P.   +2 more
core   +1 more source

Long life, high speed, thrust-load ball bearings [PDF]

open access: yes, 1975
Long-term bearing operation at three million DN can be achieved with high degree of reliability using full combination of sophisticated but currently available state-of-the-art bearing materials and designs, lubricants, and lubricating ...
Bamberger, E. N.   +2 more
core   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

PA MBP - firm production, high quality

open access: yesЛитьë и металлургия, 2000
.
E. S. Ameliantchik
doaj  

Animals bearing malignant grafts reject normal grafts that express through gene transfer the same antigen. [PDF]

open access: yes, 1990
Breaking the state of immunological unresponsiveness of tumor-bearing individuals to cancer is a prerequisite for active or passive tumor-specific immunotherapy.
Koeppen, H   +5 more
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy