Results 41 to 50 of about 19,374 (297)

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source

Review on Tribological and Vibration Aspects in Mechanical Bearings of Electric Vehicles: Effect of Bearing Current, Shaft Voltage, and Electric Discharge Material Spalling Current

Lubricants
Electric motors play a decisive role in electric vehicles by converting electrical energy into mechanical motion across various drivetrain components.
Rohan Lokhande, Sitesh Kumar Mishra, Deepak Ronanki, Piyush Shakya, Vimal Edachery, Lijesh Koottaparambil   +5 more
doaj   +1 more source

Bidirectional Current WP and CBAR Neural Network Model-Based Bearing Fault Diagnosis

IEEE Access, 2023
In the era of artificial intelligence, the development of an efficient bearing, fault diagnosis method is of vital importance to ensure smooth production operations and avoid major economic losses.
Jianguang Zhu, Tang Liu
doaj   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Wind Turbine Generator Reliability: An Exploration of the Root Causes of Generator Bearing Failures [PDF]

, 2013
Increasing the availability of multi-megawatt wind turbines (WT) is necessary if the cost of energy generated by wind is to be reduced. Reliability surveys have shown that WT generator bearings have a relatively high failure rate, with failures happening
WHITTLE, MATTHEW
core  

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

A Common-Mode Shorting Network to Reduce Common-Mode Excitation of Three-Phase Two-Level Electric Drives

IEEE Open Access Journal of Power and Energy, 2023
Common-mode voltage and current in an electric machine are undesirable. Although the strategic placement of a common-mode inductor and dc input side capacitors may reduce the common-mode current produced by an electric drive system, the effectiveness of ...
Harshita Singh, Scott D. Sudhoff
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Changes in Surface Topography and Light Load Hardness in Thrust Bearings as a Reason of Tribo-Electric Loads

Lubricants
The article focuses on the findings of endurance tests on thrust bearings. In addition to the mechanical load (axial load: 10 ≤ C0/P ≤ 19, lubrication gap: 0.33 µm ≤ h0 ≤ 1.23 µm), these bearings are also exposed to electrical loads (voltage: 20 Vpp ≤ U0
Simon Graf, Oliver Koch
doaj   +1 more source