Results 61 to 70 of about 19,374 (297)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Influence of Electric Discharges on Bearings of Electric Machines

open access: yesAdvances in Electrical and Electronic Engineering, 2006
I the last time many articles were found out discussed about shaft voltage, bearing currents and their influence on lifetime and reliability of electric machines bearings.
Karel Chmelik, Vaclav Cech, Jiri Foldyna
doaj  

Bearing voltages and currents

open access: yes, 2023
Diplomová práce se zabývá problematikou ložiskových napětí a proudů ve strojích napájených z měniče frekvence. Cílem je vyhodnocení měření na motoru typu DK0BZ 0610-4X firmy VEM Sachsenwerk Gmbh. Práce je rozdělena do 3 částí.
Kozojed, Josef
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Influence of Electric Discharges on Bearings of Electric Machina

open access: yesAdvances in Electrical and Electronic Engineering, 2008
Bearing currents are one of cause’s bearings faults. The character of a lubricator belongs to main factor influencing an inception of bearing currents. We have analyzed the electric character variety kind of lubricators; the influence of lubricators on a
Jiri Foldyna   +2 more
doaj  

Bearing Currents of Driving Machines in Drives with Semiconductor Transformers

open access: yes, 2016
Васильев Богдан Юрьевич, канд. техн. наук, доцент кафедры «Электроэнергетика и электромеханика», Санкт-Петербургский горный университет, г. Санкт-Петербург; vasilev.bu@yandex.ru. Козярук Анатолий Евтихиевич, д-р техн.
Козярук, А.Е.   +3 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Measurement of Direct Current Voltage Causing Electrical Pitting

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2010
It is widely known that electrical pitting occurs when an electrical current is passed through a ball or roller bearing. The authors have investigated critical electrical current density causing electrical pitting and have shown that it occurs in a ball ...
Shoji NOGUCHI   +2 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Measuring bearing currents

open access: yes, 2005
This thesis deals with bearing current detection. It focuses on electric motors driven by variable speed converters. Established techniques for bearing current detection were studied and modified to suit the investigated detecting requirement.
Marinov, Pavlik   +1 more
core   +1 more source

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