Results 81 to 90 of about 165,615 (260)
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Analysis and Non-Invasive Diagnostics of Bearing Faults in Three-Phase Induction Motors
Engineering ProceedingsThis article focuses on the analysis and non-invasive online diagnostics of the operating condition of bearings integrated into three-phase squirrel cage induction motors, an electric machine that, due to its construction and operational characteristics,
Juan Barreno +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Multiple-fault detection methodology based on vibration and current analysis applied to bearings in induction motors and gearboxes on the kinematic chain [PDF]
, 2016 © 2016 Juan Jose Saucedo-Dorantes et al. Gearboxes and induction motors are important components in industrial applications and their monitoring condition is critical in the industrial sector so as to reduce costs and maintenance downtimes.
Delgado Prieto, Miquel +4 more
core +2 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Optimization of resistance spot welding parameters for microalloyed steel sheets
Open Engineering, 2016 The paper presents the results of resistance spot welding of hot-dip galvanized microalloyed steel sheets used in car body production. The spot welds were made with various welding currents and welding time values, but with a constant pressing force of ...
Viňáš Ján +2 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Bearing Fault Detection and Recognition From Supply Currents With Decision Trees
IEEE AccessThis paper considers the tasks of detecting and recognizing bearing faults in electric motors from the signals collected from supply currents, using machine learning techniques. In particular, following recent trends in AI, the main point of interest was
Giovanni Briglia +3 more
doaj +1 more source
secCl is a cys-loop ion channel necessary for the chloride conductance that mediates hormone-induced fluid secretion in Drosophila [PDF]
, 2019 Organisms use circulating diuretic hormones to control water balance (osmolarity), thereby avoiding dehydration and managing excretion of waste products.
Dent, J. +6 more
core +2 more sources
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source