Results 91 to 100 of about 12,916,031 (272)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Calculation of circulating bearing currents in machines of inverter-based drive systems

open access: yes, 2004
The high-frequency circulating bearing current that may occur in machines of inverter-based drive systems can be described by an eddy-current model. The parameters of an equivalent circuit are derived from the model. The ratio between bearing current and
Mütze, A.   +4 more
core   +2 more sources

Design, Modeling and Control of Magnetic Bearings for a Ring-Type Flywheel Energy Storage System

open access: yesEnergies, 2016
This study is concerned with the magnetic force models of magnetic bearing in a flywheel energy storage system (FESS). The magnetic bearing is of hybrid type, with axial passive magnetic bearing (PMB) and radial hybrid magnetic bearing (HMB). For the PMB,
Chow-Shing Toh, Shyh-Leh Chen
doaj   +1 more source

Measuring of electrical currents, voltage and resistance of an axial bearing

open access: yes, 2021
Bearing currents induced in electrical motors driven with fast switching power electronic inverters lead to bearing surface damages on the raceway. This may be the case especially when the rotor is electrically connected to the earth potential of the ...
Safdarzadeh, Omid   +5 more
core   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Analysis and Non-Invasive Diagnostics of Bearing Faults in Three-Phase Induction Motors

open access: yesEngineering Proceedings
This article focuses on the analysis and non-invasive online diagnostics of the operating condition of bearings integrated into three-phase squirrel cage induction motors, an electric machine that, due to its construction and operational characteristics,
Juan Barreno   +2 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Bearing Fault Detection and Recognition From Supply Currents With Decision Trees

open access: yesIEEE Access
This paper considers the tasks of detecting and recognizing bearing faults in electric motors from the signals collected from supply currents, using machine learning techniques. In particular, following recent trends in AI, the main point of interest was
Giovanni Briglia   +3 more
doaj   +1 more source

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