Results 91 to 100 of about 898,382 (289)

Analysis and Non-Invasive Diagnostics of Bearing Faults in Three-Phase Induction Motors

Engineering Proceedings
This article focuses on the analysis and non-invasive online diagnostics of the operating condition of bearings integrated into three-phase squirrel cage induction motors, an electric machine that, due to its construction and operational characteristics,
Juan Barreno, Fernando Bento, Antonio J. Marques Cardoso   +2 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Optimization of resistance spot welding parameters for microalloyed steel sheets

Open Engineering, 2016
The paper presents the results of resistance spot welding of hot-dip galvanized microalloyed steel sheets used in car body production. The spot welds were made with various welding currents and welding time values, but with a constant pressing force of ...
Viňáš Ján, Kaščák Ľuboš, Greš Miroslav   +2 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Bearing Fault Detection and Recognition From Supply Currents With Decision Trees

IEEE Access
This paper considers the tasks of detecting and recognizing bearing faults in electric motors from the signals collected from supply currents, using machine learning techniques. In particular, following recent trends in AI, the main point of interest was
Giovanni Briglia, Fabio Immovilli, Marco Cocconcelli, Marco Lippi   +3 more
doaj   +1 more source

Bearing Currents of Driving Machines in Drives with Semiconductor Transformers

, 2016
Васильев Богдан Юрьевич, канд. техн. наук, доцент кафедры «Электроэнергетика и электромеханика», Санкт-Петербургский горный университет, г. Санкт-Петербург; vasilev.bu@yandex.ru. Козярук Анатолий Евтихиевич, д-р техн.
Козярук, А.Е., Васильев, Б.Ю., Kozyaruk, A.E., Vasilev, B.Yu.   +3 more
core   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

WLI, XPS and SEM/FIB/EDS Surface Characterization of an Electrically Fluted Bearing Raceway

Lubricants
Electrical bearing currents may disturb the performance of the bearings via electro-corrosion if they surpass a limit of ca. 0.1 to 0.3 A/mm2. A continuous current flow, or, after a longer time span, an alternating current or a repeating impulse-like ...
Omid Safdarzadeh, Alireza Farahi, Andreas Binder, Hikmet Sezen, Jan Philipp Hofmann   +4 more
doaj   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source