Results 51 to 60 of about 998,913 (292)
A finite-element approach for the analysis of pin-bearing failure of composite laminates [PDF]
Fracture and Structural Integrity, 2014 In this paper, a numerical home-made finite element model for the failure analysis of bolted joints between fiber-reinforced composite laminates is presented.
Michele Marino +2 more
doaj +2 more sources
Geofluids, 2022 This paper presents an experimental investigation of acoustic emission (AE) time-frequency characteristics of a water-bearing sandstone specimen in a conventional uniaxial compression test.
Hui-qiang Duan +2 more
doaj +1 more source
Study on Mechanical Bearing Strength and Failure Modes of Composite Materials for Marine Structures
Journal of Marine Science and Engineering, 2021 With the gradual application of composite materials to ships and offshore structures, the structural strength of composites that can replace steel should be explored.
Dong-Uk Kim +2 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
EnergiesIndustrial electric motors powered by variable frequency drives (VFDs) offer better controllability as compared to the conventional sinusoid-fed motors. However, the switching transients of VFDs induce shaft voltage in electric motors, which can lead to ...
Zuhair Abbas, Arifa Zahir, Jin Hur
doaj +1 more source
MATEC Web of Conferences, 2017 The present paper is focused on the bearing stress at failure of double-lap woven fabric kenaf fiber reinforced polymer (KFRP) hybrid bonded-bolted joints in experimental frameworks.
Lee Sim Yee, Ahmad Hilton
doaj +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Experimental investigation of woven fabric cfrp bolted joints: parametric study [PDF]
, 2016 Present paper comprises a wide ranging experimental study of mechanically fastened woven CFRP using double-lap joint (DLJ) configurations. Details of the bolted joint materials and its configurations are given.
Ahmad, Hilton
core +1 more source