Results 71 to 80 of about 137,028 (317)

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Analysis, Mathematical Model and Selected Simulation Research of the GNSS Navigation Receiver Correlator

open access: yesMATEC Web of Conferences, 2018
The article presents a mathematical model describing the physical phenomena occurring in the GNSS radio receiver. The main subunit which focused attention was the system of GNSS receiver correlator.
Setlak Lucjan, Kowalik Rafał
doaj   +1 more source

A Novel Fault Diagnosis Method Based on Noise-Assisted MEMD and Functional Neural Fuzzy Network for Rolling Element Bearings

open access: yesIEEE Access, 2018
To solve the problem in which the auxiliary white-noise parameters need to be artificially selected in a noise-assisted multivariate empirical mode decomposition (NA-MEMD) and considering the fact that obtaining a large number of typical fault samples in
Sheng Liu, Yue Sun, Lanyong Zhang
doaj   +1 more source

PC-based aviation training devices (PCATDs): research, development and certification [PDF]

open access: yes, 2011
This paper examines the development of two PCATD’s (one helicopter, one fixed-wing) and their eventual certification by CAA. Certification has demonstrated the potential these devices have for aviation training in New Zealand.
Gilbey, Andrew   +3 more
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

In vivo tumor detection with combined MR–Photoacoustic-Thermoacoustic imaging [PDF]

open access: yesJournal of Innovative Optical Health Sciences, 2016
Here, we report a new method using combined magnetic resonance (MR)–Photoacoustic (PA)–Thermoacoustic (TA) imaging techniques, and demonstrate its unique ability for in vivo cancer detection using tumor-bearing mice.
Lin Huang   +9 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Fault Diagnosis of Water Lubricated Stern Bearing based on BP Neural Network

open access: yesJixie chuandong, 2015
The water lubricated stern bearing is a special bearings which widely used in ships and other water vessels sail propulsion system,because of its work environment is of great uncertainty,the product is prone to various of failures,once the failure ...
Liang Feng, Zhang Dandan, Zhang Ronghua
doaj  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

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