Results 61 to 70 of about 422,318 (308)
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Processing and fluid flow characteristics of hot isostatically pressed porous alumina for aerostatic bearing applications [PDF]
Despite their well known superior load and stiffness characteristics, the wide-spread use of porous aerostatic bearings in preference to other bearing types has been hampered by difficulties in controlling the permeability of the porous material during
Kwan, Y. B. P
core
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Effect of Relative Density and Stress Level on the Bearing Capacity of Footings on Sand
The design of shallow foundations relies on bearing capacity values calculated using empirical procedures that are based in part on solutions obtained using the method of characteristics, which assumes a soil that is perfectly plastic following an ...
Loukidis, D, Salgado, Rodrigo
core
A Self aligning spherical journal bearing is a plain bearing which has spherical surface contact that can be applied in high power industrial machinery. This type of bearing can accommodate a misalignment problem.
Gu, Fengshou +7 more
core +1 more source
Running-in wear modeling of honed surface for combustion engine cylinder liners [PDF]
The texture change during running-in alters the performance and efficiency of a tribo-mechanical system. During mass production of cylinder liners, a final finishing stage known as ‘‘plateau honing’’ is commonly added to reduce the running-in wear ...
EL MANSORI, Mohamed +3 more
core +1 more source
Effect of Surface Roughness on Characteristics of Textured Hydrodynamic Bearings
For a radial hydrodynamic bearing with surface micro texture,the Gauss random rough surface is used to simulate the surface roughness of the bearing bush.
Hongtao Wang, Shaolin Zhang, Shuai Yang
doaj
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Rolling contact fatigue performance of HIPed Si3N4 with different surface roughness
Accelerated rolling contact fatigue four-ball tests were performed on hot isostatically pressed (HIPed) silicon nitride/steel contacts under lubricated condition using a PLINT TE92/HS microprocessor controlled rotary tribometer at a maximum compressive ...
Kang, J +5 more
core +1 more source

