Results 61 to 70 of about 422,318 (308)

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Processing and fluid flow characteristics of hot isostatically pressed porous alumina for aerostatic bearing applications [PDF]

open access: yes, 1996
Despite their well known superior load and stiffness characteristics, the wide-spread use of porous aerostatic bearings in preference to other bearing types has been hampered by difficulties in controlling the permeability of the porous material during
Kwan, Y. B. P
core  

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Effect of Relative Density and Stress Level on the Bearing Capacity of Footings on Sand

open access: yes, 2010
The design of shallow foundations relies on bearing capacity values calculated using empirical procedures that are based in part on solutions obtained using the method of characteristics, which assumes a soil that is perfectly plastic following an ...
Loukidis, D, Salgado, Rodrigo
core  

A Comparative Study of the Monitoring of a Self Aligning Spherical Journal using Surface Vibration, Airborne Sound and Acoustic Emission

open access: yes, 2012
A Self aligning spherical journal bearing is a plain bearing which has spherical surface contact that can be applied in high power industrial machinery. This type of bearing can accommodate a misalignment problem.
Gu, Fengshou   +7 more
core   +1 more source

Running-in wear modeling of honed surface for combustion engine cylinder liners [PDF]

open access: yes, 2013
The texture change during running-in alters the performance and efficiency of a tribo-mechanical system. During mass production of cylinder liners, a final finishing stage known as ‘‘plateau honing’’ is commonly added to reduce the running-in wear ...
EL MANSORI, Mohamed   +3 more
core   +1 more source

Effect of Surface Roughness on Characteristics of Textured Hydrodynamic Bearings

open access: yesJixie chuandong, 2022
For a radial hydrodynamic bearing with surface micro texture,the Gauss random rough surface is used to simulate the surface roughness of the bearing bush.
Hongtao Wang, Shaolin Zhang, Shuai Yang
doaj  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Rolling contact fatigue performance of HIPed Si3N4 with different surface roughness

open access: yes, 2001
Accelerated rolling contact fatigue four-ball tests were performed on hot isostatically pressed (HIPed) silicon nitride/steel contacts under lubricated condition using a PLINT TE92/HS microprocessor controlled rotary tribometer at a maximum compressive ...
Kang, J   +5 more
core   +1 more source

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