Results 51 to 60 of about 5,384,913 (273)

Technical Trend of Friction Reduction in Engine Bearings

open access: yesTribology Online, 2017
Currently, the demand for improved fuel consumption rates in automobiles has increased because of growing concerns related to global warming and energy conservation.
Shu Kamiya, Toru Desaki
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Plain bearing stresses due to forming and oil film pressure

open access: yes, 2009
This paper describes a methodology for assessing critical stress ranges arising in automotive plain bearings during engine operations. An industry-produced and run simulation program provides information on oil film pressure and overall bearing ...
Burke-Veliz, A.   +5 more
core   +2 more sources

MATHEMATICAL MODEL OF COMPRESSIBLE MICROPOLAR HYDRODYNAMIC LUBRICATION FOR RADIAL BEARING WITH ADAPTED PROFILE OF ITS SURFACE

open access: yesAdvanced Engineering Research, 2011
The analytical hydrodynamic calculations of the radial bearing with the adapted profile of its contact surface are made. Some optimal intervals of the nondimensional parameters typical for the compressible micropolar lubricants, as well as the parameter ...
Murman A. Mukutadze
doaj  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

MATHEMATICAL MODEL OF COMPRESSIBLE MICROPOLAR HYDRODYNAMIC LUBRICATION FOR RADIAL BEARING WITH ADAPTED PROFILE OF ITS SURFACE

open access: yesВестник Донского государственного технического университета, 2018
The analytical hydrodynamic calculations of the radial bearing with the adapted profile of its contact surface are made. Some optimal intervals of the nondimensional parameters typical for the compressible micropolar lubricants, as well as the parameter ...
Murman A. Mukutadze
doaj  

Experimental Study on Water Lubrication Characteristics of Full-Flat Thrust Bearing with Partial Water-Repellent Surface

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2013
In this study, a flat thrust bearing is developed by active exploiting the slip flow generated on a water-repellent surface. In order to produce a load, this bearing has a structure that generates a pressure flow by using the discontinuity of shear flow ...
Akitoshi TAKEUCHI, Yukio KITAMURA
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

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