Results 121 to 130 of about 206,251 (288)
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Scientific ReportsMining stress induces deformation and fracture of the overlaying rock, which will result in water filling the separation layer if the aquifer finds access to abscission space along the fracture channels.
Haiyan Yang +7 more
doaj +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
The Influence of Inverter,s Output Voltage du/dt on the Motor and Its Filter Design
Kongzhi Yu Xinxi Jishu, 2012 This paper studies the influence of inverter’s output voltage du/dt on the end voltage and bearing current of the motor, sets up the motor high-frequency model in PSpice and stimulates waveforms of the end voltage.
CHEN Tao +4 more
doaj
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Active nutation controller [PDF]
, 1980 An apparatus is described for controlling nutation motion in a spinning body, comprised of an angular accelerometer with its input axis perpendicular to the spin axis of the body, a flywheel with an axis of rotation perpendicular to the axis of the ...
Donohue, J. H., Hoffman, H. C.
core +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Focus drive mechanism for the IUE scientific instrument [PDF]
, 1977 A compact, lightweight mechanism was developed for in-orbit adjustment of the position of the secondary mirror (focusing) of the International Ultraviolet Explored telescope. This device is a linear drive with small (.0004 in.) and highly repeatable step
Dennis, T. B., Jr., Devine, E. J.
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
IEEE AccessIn various variable speed applications with power converters, failures in the bearings caused by common mode voltage (CMV) have been frequently reported. This study investigates space vector modulation (SVM)-based strategies for reducing CMV in a modular
Chengjun Tang +2 more
doaj +1 more source