Results 101 to 110 of about 205,989 (300)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Computerized system for translating a torch head [PDF]

, 1978
The system provides a constant travel speed along a contoured workpiece. It has a driven skate characterized by an elongated bed, with a pair of independently pivoted trucks connected to the bed for support. The trucks are mounted on a contoured track of
Bruce, M. M., Jr., Gard, L. H., Ives, R. E., Pryor, P. P., Jr., Wall, W. A., Jr.   +4 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Analysis of capacitive discharges in motor bearings under different operation conditions

IET Electric Power Applications
Despite being a well‐known problem, bearing faults are still one of the major challenges that the industry face. The growing use of voltage source inverters imposed the alertness of possible bearing damage due to their high‐frequency signals.
Sara Jammoul, Remus Pusca, Raphael Romary, Guillaume Lefevre, Nicolas Voyer, Guilherme Bueno Mariani   +5 more
doaj   +1 more source

Distributed PV Bearing Capacity Assessment Method Based on Source–Load Coupling Scenarios

Energies
To address the insufficient consideration of system static voltage stability and PV–load coupling in distributed photovoltaic (PV) hosting capacity assessment, this study first investigates the impact of distributed PV integration on power system ...
Yalu Sun, Zhou Wang, Yongcheng Liu, Yi Jiang, Yalong Li   +4 more
doaj   +1 more source

Enhancing Bearing Fault Diagnosis in Induction Motors: A Novel Approach Leveraging Synchronized Deviation of Instantaneous Frequency of Voltage and Current [PDF]

AUT Journal of Electrical Engineering
Current-based methods for bearing fault diagnosis primarily rely on analyzing the current signal, leading to challenges in detecting fault frequencies due to their low magnitude amid the noise in the current spectrum.
Somaye Nazari, Jamal Moshtagh
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Helium additions to MIG shielding gas - an economic option? [PDF]

, 2011
An investigation has been carried out to establish the technical and economic benefits of adding two levels of helium to a normal shielding gas. Technically no adverse issues were established using the two levels of helium, and the most significant ...
Galloway, Alexander, Gillies, Andrew, McPherson, Norman   +2 more
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Robust Fuzzy Control of an Active Magnetic Bearing Subject to Voltage Saturation

IEEE Transactions on Control Systems Technology, 2010
Based on a recently proposed model for the active-magnetic-bearing (AMB) switching mode of operation, this paper presents a robust Takagi-Sugeno-model-based fuzzy-control strategy to stabilize the AMB with fast response speed subject to control-voltage saturation and parameter uncertainties.
Du, Haiping, Zhang, Nong, Ji, Jinchen, Gao, Wei   +3 more
openaire   +3 more sources