Results 101 to 110 of about 1,644,975 (282)

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up

Molecular Oncology, EarlyView.
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani, Laura Mariën, Caro De Weerdt, Sanne Wouters, Laure‐Anne Teuwen, Hans Prenen, Katleen Janssens, Timon Vandamme   +7 more
wiley   +1 more source

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source

Analysis of capacitive discharges in motor bearings under different operation conditions

IET Electric Power Applications
Despite being a well‐known problem, bearing faults are still one of the major challenges that the industry face. The growing use of voltage source inverters imposed the alertness of possible bearing damage due to their high‐frequency signals.
Sara Jammoul, Remus Pusca, Raphael Romary, Guillaume Lefevre, Nicolas Voyer, Guilherme Bueno Mariani   +5 more
doaj   +1 more source

Energy optimization of multiprocessor systems on chip by voltage selection

, 2007
Dynamic voltage selection and adaptive body biasing have been shown to reduce dynamic and leakage power consumption effectively. In this paper, we optimally solve the combined supply voltage and body bias selection problem for multiprocessor systems with
Eles, Petru Ion,, Peng, Zebo,, Peng, Zebo, Schmitz, M.T.,, Schmitz, Marcus, Al-Hashimi, Bashir M., Andrei, Alexandru,, Andrei, Alexandru, Eles, Pertu, Al, Hashimi B.M.,   +9 more
core   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source

A Comparative Analysis of Space Vector Modulation-Based Common Mode Voltage Reduction Strategies in a Modular Multilevel Converter

IEEE Access
In various variable speed applications with power converters, failures in the bearings caused by common mode voltage (CMV) have been frequently reported. This study investigates space vector modulation (SVM)-based strategies for reducing CMV in a modular
Chengjun Tang, Jian Zhao, Torbjorn Thiringer   +2 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Multiphysics-Coupled Load-Bearing Capacity of Piezoelectric Stacks in Low-Temperature Environments

Sensors
Under low-temperature conditions, the load-bearing capacity of piezoelectric stacks arises from coupled thermo-electro-mechanical interactions, with temperature fluctuations, compressive prestress, and excitation voltage critically modulating performance.
Yang Li, Yongping Zheng, Leipeng Song, Zhefan Yao, Hui Zhang, Yonglin Wang, Zhengshun Fei, Xiaozhou Xu, Xinjian Xiang   +8 more
doaj   +1 more source

On a New Type of Inverter-Induced Bearing Current in Large Drives with One Journal Bearing

, 2008
We report on a new type of inverter-induced bearing current that can occur with large inverter-based drive systems with one journal bearing. This current is a variation of the "high-frequency circulating" bearing current type which has been described by ...
HASH(0x55a67f63c900), Muetze, Annette
core   +1 more source