Results 41 to 50 of about 55,867 (251)

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Investigation of the Static Breakdown Voltage of the Lubricating Film in a Mechanical Ball Bearing

, 2018
In this paper, the current pulse (discharge) activity in a small bearing is investigated when current-limited DC voltages of different levels are applied to the shaft under varying rotational speeds and mechanical loads.
Abhishek Joshi, Jörgen Blennow
core   +1 more source

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters, Ji Yun Tark, Tiffany M. Chambers, Tania A. Desrosiers, Michael E. Scheurer, Charles Shumate, Wendy N. Nembhard, Mahsa M. Yazdy, Eirini Nestoridi, Amanda E. Janitz, Jean Paul Tanner, Russell S. Kirby, Jason L. Salemi, Yao Yu, Chad D. Huff, Sharon E. Plon, Philip J. Lupo, Jeremy M. Schraw   +17 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Measuring of electrical currents, voltage and resistance of an axial bearing

, 2021
Bearing currents induced in electrical motors driven with fast switching power electronic inverters lead to bearing surface damages on the raceway. This may be the case especially when the rotor is electrically connected to the earth potential of the ...
Safdarzadeh, Omid, Andreas Binder, Weicker, Martin, Martin Weicker, Omid Safdarzadeh, Binder, Andreas   +5 more
core   +1 more source

The Discharge and Corrosion Behavior of Al Anodes with Different Purity in Alkaline Solution

International Journal of Electrochemical Science, 2020
The replacement of high purity Al anodes with low purity Al meanwhile maintaining low self-corrosion and high electrochemical activity is of significance for commercial application of Al-air battery. In this paper, the discharge and corrosion behavior of
G.S. Peng, J. Huang, Y.C. Gu, G.S. Song
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Parallel distributed compensation for voltage controlled active magnetic bearing system using integral fuzzy model [PDF]

, 2018
Parallel Distributed Compensation (PDC) for current-controlled Active Magnetic Bearing System (AMBS) has been quite effective in recent years. However, this method does not take into account the dynamics associated with the electromagnet. This limits the
Razvarz, Sina, Gegov, A, Gegov, Alexander, Tatchum, M, Razvarz, S, Raheleh Jafari, Jafari, R, Alexander Gegov, Martial Tatchum, Sina Razvarz, Jafari, Raheleh, Tatchum Kamkumo, Guy Martial   +11 more
core   +1 more source