Results 61 to 70 of about 1,644,975 (282)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

A hybrid multilevel converter for medium and high voltage applications [PDF]

, 2010
This paper investigates the suitability of the hybrid multilevel converter for medium and high voltage application. The converter operation, modulation, and capacitor voltage balancing method are described in detail.
Ahmed, Khaled, Adam, Grain Philip, Finney, Stephen, Singh, N.K., Williams, Barry   +4 more
core   +2 more sources

Investigation of the Static Breakdown Voltage of the Lubricating Film in a Mechanical Ball Bearing

, 2013
In this paper, the current pulse (discharge) activity in a small bearing is investigated when current-limited DC voltages of different levels are applied to the shaft under varying rotational speeds and mechanical loads.
Blennow, Jörgen,, Joshi, Abhishek,
core   +1 more source

Research on Mechanism and Suppression Technique of Metro Vehicles Traction Motor Bearing Electrocorrosion

机车电传动, 2019
In order to solve the problem of electrocorrosion of traction motor bearings of metro vehicles, the fault mechanism was analyzed, and the solutions were put forward and verified.
Guanglin YAN, Yongjian ZHI, Xiang CHEN, Wuling ZHONG   +3 more
doaj  

Experimental Investigation of the Impact of Cable Length and Type on Motor Overvoltages, Shaft Voltage, and Bearing Currents in PWM-Inverter-Fed Drive Systems

Machines
Fast-switching transients and high dv/dt associated with PWM inverters exacerbate the reflected-wave effects in the motor feeder cable. This leads to higher motor-side overvoltages, which increase the stress on the motor winding insulation, potentially ...
Fawzy A. Abdo, Mehmet Güleç, Kotb B. Tawfiq, Peter Sergeant   +3 more
doaj   +1 more source

Voltage dip immunity of equipment in installations [PDF]

, 2007
This paper presents the status of the work in C4.110, a joint working group by CIGRE, CIRED and UIE. The scope of the working group is to gather technical knowledge on the immunity of equipment, installations and processes against voltage dips, and to ...
Stephens, M., Djokic, Sasa, Bollen, M., Romero Gordon, Jose, Stockman, K., McEachern, A.   +5 more
core  

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

Modelling of high frequency bearing voltage for dual‐winding permanent magnet synchronous generators

IET Electric Power Applications
The modelling and analysis of high‐frequency bearing voltage are of great significance to the assessment and mitigation of the electrical erosion risk in wind power systems.
Zhihao Li, Ruifang Liu, Liangliang Zhang, Weili Li, Shulin Li, Xin Huang   +5 more
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source