Results 61 to 70 of about 204,972 (289)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Reduction of Shaft Voltage of IPMSM According to the Shape of the Novel Shield Ring

open access: yesIEEE Access
Recently, the motor drive system of electric vehicles (EVs) has been increased to high voltage to enhance the output and efficiency of the motor. However, higher voltage exacerbates common-mode voltage (CMV), which is the main cause of bearing faults ...
Jun-Kyu Kang   +3 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Characteristic Analysis and Simulated Test of Hybrid Bearing with the Introduction of Piezoelectric Controller

open access: yesShock and Vibration, 2016
A novel hybrid bearing with the introduction of piezoelectric controller and tilting pads to control vibration actively is proposed in this paper, and the feasibility of this scheme is verified by theoretical calculation and experimental data.
Runlin Chen   +4 more
doaj   +1 more source

Apparatus for aiding a pilot in avoiding a midair collision between aircraft [PDF]

open access: yes, 1973
An apparatus for aiding a pilot in avoiding a midair collision between aircraft is described. A protected aircraft carries a transmitter, a transponder, a receiver, and a data processor; and an intruding cooperating aircraft carries a transponder.
Couch, R. H., Schrader, J. H.
core   +1 more source

A cascaded H-bridge BLDC drive incorporating battery management [PDF]

open access: yes, 2007
A multilevel BLDC drive is proposed using cascaded H-bridges with isolated sources to provide superior output waveforms and reduced current ripple whilst incorporating observer based SoC estimation.
Bingham, Chris   +3 more
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

A schistosome [beta] subunit remodels inactivation of a calcium channel _via_ an N-terminal polyacidic motif [PDF]

open access: yes, 2010
The beta subunit of high voltage-activated Ca (Cav) channels targets the pore forming [alpha]~1~ subunit to the plasma membrane and defines the biophysical phenotype of the Cav channel complex. Cav channel inactivation following activation and opening is
Robert M. Greenberg   +1 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Investigation of an axial-excursion transducer for squeeze-film bearings [PDF]

open access: yes
Resonant frequencies and characteristic bearing cone motion of axial-excursion transducer for squeeze-film gas bearing - drive voltage, preload, bearing mass, and mounting ring ...
Kissinger, C.   +2 more
core   +1 more source

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