Results 191 to 200 of about 1,122,872 (306)
openaire +2 more sources
Genetic and pharmacological inhibition of SLC11A1 functioning as an H+/Fe2+ antiporter–mediated lysosomal iron accumulation in microglia promotes lysosomal lumen acidification, increases CTSD expression, enhances lysosomal myelin debris uptake and degradation, and promotes repair following white matter stroke. ABSTRACT White matter stroke (WMS) results
Lingling Qiu +11 more
wiley +1 more source
Self-Objectification, Body Surveillance, and Body Shame Across Countries: A Comparison Between US, UK, Belgian, Israeli, and Thai Women. [PDF]
Wollast R +5 more
europepmc +1 more source
Versatile CRISPR‐Cas Tools for Gene Regulation in Zebrafish via an Enhanced Q Binary System
This study introduces CRISPR‐Q, a transgenic CRISPR‐Cas system leveraging the QFvpr/QUAS binary expression platform in zebrafish. CRISPR‐Q overcomes previous challenges in achieving stable and efficient gene regulation. By enabling precise spatiotemporal control of transcript knockdown (CRISPR‐QKD) and gene activation (CRISPR‐Qa), it provides a ...
Miaoyuan Shi +13 more
wiley +1 more source
Filters, algorithms, and the "imagination tax": the dilemma of aesthetic self-objectification among Chinese young women on social media. [PDF]
Sun H, Wu R.
europepmc +1 more source
Lipid overload suppresses SREBF2‐mediated FNTB expression, leading to defective Lamin A maturation and nuclear envelope instability. This nuclear catastrophe triggers a pro‐fibrotic senescence program in cardiomyocytes. Notably, restoring nuclear integrity via AAV9‐based gene therapy effectively attenuates cardiac remodeling, identifying the ...
Yuxiao Chen +16 more
wiley +1 more source
Light Sources in Hyperspectral Imaging Simultaneously Influence Object Detection Performance and Vase Life of Cut Roses. [PDF]
Kim YT, Ham JY, In BC.
europepmc +1 more source
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao +36 more
wiley +1 more source
Heavy metal in cosmetics and its risk to future generation in remote area of Azad Jammu and Kashmir Trarkhel District Sudhnoti. [PDF]
Bashir H +9 more
europepmc +1 more source

