Results 51 to 60 of about 25,297 (306)

Concrete spirituality

open access: yesHTS Teologiese Studies/Theological Studies, 2014
This article reflects on a number of liturgical innovations in the worship of Melodi ya Tshwane, an inner-city congregation of the Uniting Reformed Church in Southern Africa (URCSA).
Johannes N.J. Kritzinger
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

A Correlational Study Examining the Relationship Between the Eurocentric, Westernized Beauty Standards and the Rejection-identification Model [PDF]

open access: yes, 2023
The Rejection-identification Model proposes that among racial minority groups, perceptions of rejection from the dominant majority group are associated with minority group identification.
Saccullo, Jocelyn L.
core  

Aspek Flora untuk Penyebutan Standar Kecantikan dalam Bahasa Sunda

open access: yesRanah: Jurnal Kajian Bahasa, 2023
The purpose of this research is to reveal the direct meaning or conceptual meaning and figurative meaning or associative meaning. The method used in this research is analytical descriptive method with data collection techniques by literature review ...
Sandi Setiawan   +3 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

The Quest for an Ideal Beauty in Toni Morrison's The Bluest Eye

open access: yesمجلة كلية التربية للبنات, 2019
In The Bluest Eye (1970), the American-African writer, Toni Morrison explores how Western standards of ideal beauty are created and propagated with and among the black community.
Maysoon Taher Muhi, Fatima Ridha
doaj  

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

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