Results 41 to 50 of about 680 (206)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Enabling the Disabled: Negotiation of Beauty in a Disabled Model Instagram Account
Mozaik HumanioraDEI (diversity, equity, and inclusivity) in the beauty industry is evident through the increasing number of disabled models. Working from the concept of Wolf’s Beauty Myth, this study aims to reveal how Jillian Mercado portrays and negotiates beauty ...
Raselly Elfa Putri, Gesang M N Putra
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Skin Lightening Among Young Adults in Ilorin West, Nigeria: Health Risks, Societal Pressures, and the Pursuit of Fairness [PDF]
Global Journal of Environmental Science & SustainabilitySkin-lightening practices are increasingly common among young adults, influenced by societal beauty standards, cultural traditions, and economic factors. However, these practices pose serious health risks, including skin damage and psychological distress.
Olaolu Bilewu +5 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
The healthy eating movement on social media and its psychological effects on body image
Frontiers in NutritionIntroductionThe present study aims to investigate the relationship between social-media pressure, the tendency to internalize standards of beauty and attractiveness associated with thin bodies, which subsequently leads to distortion of body shape ...
Alina Zaharia, Iulia Gonța
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
FarabiThis study aims to analyze the negotiation of digital beauty standards and body image formation among female students at IAIN Sultan Amai Gorontalo.
Nuraisah +2 more
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Columbia Social Work Review, 2019 Black women are particularly vulnerable to the effects of European standards of beauty, because these standards emphasize skin colors and hair types that exclude many black women, especially those of darker skin.
Susan L. Bryant
doaj