Results 151 to 160 of about 9,962,231 (339)

Tau positron emission tomographic imaging in aging and early Alzheimer disease

Annals of Neurology, 2016
Keith A. Johnson, A. Schultz, R. Betensky, J. Becker, J. Sepulcre, D. Rentz, E. Mormino, J. Chhatwal, R. Amariglio, K. Papp, G. Marshall, M. Albers, S. Mauro, L. Pepin, Jonathan Alverio, Kelly Judge, Marlie Philiossaint, T. Shoup, Daniel L. Yokell, B. Dickerson, T. Gómez-Isla, B. Hyman, N. Vasdev, R. Sperling   +23 more
semanticscholar   +1 more source

Psychedelics, entactogens and psychoplastogens for depression and related disorders

British Journal of Pharmacology, EarlyView.
Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
wiley   +1 more source

Evaluation of preclinical antipsychotic models used to support first‐in‐human clinical trials

British Journal of Pharmacology, EarlyView.
Abstract Schizophrenia is regarded as a complex and heterogeneous psychiatric disorder, characterised by diverse symptoms and comorbidities, which complicate both clinical management and drug development. Current pharmacological treatment, primarily based on dopamine D2 receptor antagonism or partial agonism, which has not markedly progressed since the
Thi Viet Ha Nguyen, Declan P. McKernan, John P. Kelly   +2 more
wiley   +1 more source

Coexistence of congenital central hypoventilation syndrome, Hirschsprung disease, and Becker muscular dystrophy

Brain and Development Case Reports, 2023
Yuki Kawashima, Satoka Akiyama, Yosuke Yamada, Masahiro Noda, Kunihiro Oba, Hirofumi Komaki, Koji Komori, Ayako Sasaki, Masashi Ogasawara   +8 more
openaire   +1 more source

The return of metabolism: biochemistry and physiology of glycolysis

Biological Reviews, EarlyView.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning, Federica Agostini, Camila Caldana, Johannes Hartl, Matthias Heinemann, Markus A. Keller, Jan Lukas Krüsemann, Costanza Lamperti, Carole L. Linster, Steffen N. Lindner, Julia Muenzner, Jens Nielsen, Zoran Nikoloski, Bettina Siebers, Jacky L. Snoep, Hezi Tenenboim, Bas Teusink, Spencer J. Williams, Mirjam M. C. Wamelink, Markus Ralser   +19 more
wiley   +1 more source

Cross-sectional and longitudinal atrophy is preferentially associated with tau rather than amyloid β positron emission tomography pathology [PDF]

, 2018
Ances, Beau M, Benzinger, Tammie L.S, Blazey, Tyler M, Christensen, John, Dincer, Aylin, Gordon, Brian A, Hornbeck, Russ C, Jackson, Kelley, McCullough, Austin, Mishra, Shruti, Morris, John C, Su, Yi   +11 more
core   +2 more sources

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

Nature Genetics, 2011
Heribert Schunkert, I. König, S. Kathiresan, M. Reilly, T. Assimes, H. Hólm, Michael H. Preuss, A. Stewart, M. Barbalić, C. Gieger, D. Absher, Z. Aherrahrou, H. Allayee, D. Altshuler, Sonia S Anand, Karl Andersen, Jeffrey L. Anderson, D. Ardissino, Stephen G. Ball, A. Balmforth, T. Barnes, D. Becker, Lewis C. Becker, Klaus Berger, J. Bis, S. Boekholdt, E. Boerwinkle, P. Braund, Morris J. Brown, M. Burnett, I. Buysschaert, J. Carlquist, Li Chen, Sven Cichon, V. Codd, Robert W Davies, G. Dedoussis, A. Dehghan, S. Demissie, Joseph M Devaney, P. Diemert, Ron Do, A. Doering, S. Eifert, N. E. Mokhtari, S. Ellis, R. Elosúa, J. Engert, Stephen E. Epstein, U. de Faire, Marcus Fischer, Aaron R. Folsom, Jennifer Freyer, B. Gigante, D. Girelli, S. Gretarsdottir, V. Gudnason, Jeffrey R. Gulcher, E. Halperin, Naomi Hammond, Stanley L Hazen, A. Hofman, B. Horne, T. Illig, C. Iribarren, Gregory T. Jones, J. Jukema, M. Kaiser, Lee M. Kaplan, J. Kastelein, K. Khaw, J. Knowles, G. Kolovou, A. Kong, R. Laaksonen, D. Lambrechts, K. Leander, G. Lettre, Mingyao Li, W. Lieb, C. Loley, A. Lotery, P. Mannucci, Seraya Maouche, N. Martinelli, Pascal P. McKeown, C. Meisinger, T. Meitinger, O. Melander, P. Merlini, V. Mooser, Thomas M. Morgan, Thomas W. Mühleisen, J. Muhlestein, T. Münzel, K. Musunuru, J. Nahrstaedt, C. Nelson, M. Nöthen, O. Olivieri, R. Patel, Chris C Patterson, Annette Peters, F. Peyvandi, L. Qu, A. Quyyumi, D. Rader, L. Rallidis, C. Rice, F. Rosendaal, Diana Rubin, V. Salomaa, M. Sampietro, Manj S. Sandhu, E. Schadt, Arne S Schäfer, A. Schillert, Stefan Schreiber, J. Schrezenmeir, Stephen M. Schwartz, D. Siscovick, Mohan Sivananthan, S. Sivapalaratnam, A. Smith, Tamara B. Smith, J. Snoep, N. Soranzo, J. Spertus, K. Stark, K. Stirrups, Monika Stoll, W. H. W. Tang, Stephanie Tennstedt, G. Thorgeirsson, G. Thorleifsson, M. Tomaszewski, A. Uitterlinden, A. V. Van rij, B. Voight, N. Wareham, George A. Wells, H. Wichmann, P. Wild, C. Willenborg, J. Witteman, Benjamin J. Wright, Shu Ye, T. Zeller, Andreas Ziegler, F. Cambien, A. H. Goodall, L. Cupples, T. Quertermous, Winfried März, C. Hengstenberg, S. Blankenberg, W. Ouwehand, A. Hall, P. Deloukas, J. Thompson, K. Stefánsson, Robert Roberts, U. Thorsteinsdóttir, C. O’Donnell, R. McPherson, Jeanette Erdmann, N. Samani   +166 more
semanticscholar   +1 more source

Influence of Abutment Shape on Implant Marginal Bone Remodeling: A Double‐Blind, Randomized 24‐Month Clinical Study

Clinical Oral Implants Research, EarlyView.
ABSTRACT Objective This study follows a 2‐year evaluation to verify marginal bone remodeling (MBR) trends associated with different abutment designs. Methods A balanced, randomised, double‐blind clinical trial with two parallel experimental arms. 68 implants were placed in 9 men and 12 women, 48.5% using the straight abutment and 51.5% the concave ...
Flavio Seijas Naya, Juan C. Bernabeu Mira, Alba Pérez Jardón, Mercedes Conde Amboage, David Peñarrocha Oltra, Fabio Camacho Alonso, Mario Pérez Sayáns   +6 more
wiley   +1 more source

One‐Year Analysis of Clinical and Radiological Outcomes of Two‐Piece Zirconia Compared to Titanium Implants: A Multicenter Prospective Randomized Clinical Trial

Clinical Oral Implants Research, EarlyView.
ABSTRACT Objectives To evaluate the clinical performance of two‐piece zirconia implants with screw‐retained abutments compared to titanium implants after 1 year of loading. Materials and Methods In this multicenter, prospective, randomized clinical trial, 61 two‐piece zirconia and 61 titanium implants were placed and restored with single crowns ...
Marc Balmer, Michael Payer, Anke Steinwender, Valentin Herber, Ronald E. Jung, Sebastian Kühl   +5 more
wiley   +1 more source

Contact Allergy to Ingredients of Hair Cosmetics Associated with Occupational and Non‐Occupational Exposure—Trends from 1995 to 2020 in Central Europe, with or without Regulation

Contact Dermatitis, EarlyView.
Among 2678 female hairdressers and 6244 female consumers with contact dermatitis suspected to be related to use of hair cosmetics, including dyes, patch tested in the IVDK between 1995 and 2020, diverging contact allergy trends were observed. In the case of toluene‐2,5‐diamine (PTD) shown in the figure, sensitization was at a stable, high level in ...
Wolfgang Uter, Jakob Ferløv Baselius Schwensen, Brunhilde Blömeke, Olaf Gefeller, Swen M. John, Cara Bieck, Steffen Schubert   +6 more
wiley   +1 more source