Results 151 to 160 of about 409,422 (304)

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Histological Response and Prognostic Factors in Gastric Adenocarcinoma Treated With Fluorouracil, Leucovorin, Oxaliplatin, and Docetaxel (FLOT) Chemotherapy: A Retrospective Single-Center Study. [PDF]

Cureus
Pereira H, Martins D, Tavares A, Amado A, Tavares A, Pereira B.   +5 more
europepmc   +1 more source

Phase 2 study of combination SPI-1620 with docetaxel as second-line advanced biliary tract cancer treatment [PDF]

, 2017
A Rai, AG Tolcher, AX Zhu, Caio Max S Rocha-Lima, David Portnoy, DP Brooks, E Gabriela Chiorean, E Suzuki, J Albores-Saavedra, J Nelson, J Valle, JE Rogers, JF Guion-Dussere, Jitendra Gandhi, L Goyal, M Yanagisawa, Manik Amin, NV Rajeshkumar, NV Rajeshkumar, P Papakostas, R Pazdur, Richard Kim, RK Jain, RL Siegel, S He, SC Lee, SY Oh, T Sasaki, T Walter, Tao Song, William P Harris   +30 more
core   +3 more sources

Diaphragm‐specific effects of L‐citrulline in mdx mice highlight its potential as adjuvant of standard therapy in Duchenne muscular dystrophy

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose The absence of the protein dystrophin in Duchenne muscular dystrophy (DMD) leads to progressive muscle weakness, failing regeneration and deregulation of nitric oxide (NO) signalling. We focused on L‐citrulline, a precursor of L‐arginine, required for NO production in muscle, which is reduced in dystrophic mdx muscle ...
Lisamaura Tulimiero, Brigida Boccanegra, Paola Mantuano, Antonietta Mele, Michela De Bellis, Roberta Lenti, Francesca Sanarica, Santa Cirmi, Elena Conte, Ornella Cappellari, Amber E. Sherrard, Ardawna Green, Mira Srinivasa, Marta L. Fiorotto, Annamaria De Luca   +14 more
wiley   +1 more source

CCAAT-enhancer binding protein delta functions as a tumor suppressor gene in acute myeloid leukemia. [PDF]

Neoplasia
Prajapati SC, Meydan C, Neelamraju Y, Wang Z, Atwood G, Paudel BB, Fan H, Dunham N, Dillon R, Gandara JA, Lee T, Sheridan C, Wang S, Zumbo P, Becker MW, Bullinger L, Carroll MP, D'Andrea RJ, Levine RL, Mason CE, Melnick AM, Zang C, Bekiranov S, Garrett-Bakelman FE.   +23 more
europepmc   +1 more source

Sorafenib for advanced and refractory desmoid tumors [PDF]

, 2018
Van Tine, Brian A.
core   +1 more source

Global Prevalence of Sexual Dysfunction in Individuals With Atopic Dermatitis and Asthma: A Systematic Review and Meta‐Analysis

Clinical &Experimental Allergy, EarlyView.
Sexual dysfunction is an often‐overlooked aspect of allergic diseases. It was more frequently reported in asthma than in atopic dermatitis and was consistently higher among females. Estimates varied by assessment approach, highlighting the need to address sexual health and standardise evaluation methods.
Suh Hyun Kim, Soeun Kim, Dongjin Yeo, Seohyun Hong, Yoon Lee, Yeona Jo, Seong H. Cho, Dong Keon Yon, Nikolaos G. Papadopoulos   +8 more
wiley   +1 more source

Elevated lactate in AML bone marrow contributes to macrophage polarization via GPR81 signaling. [PDF]

Blood Adv
Soto CA, Lesch ML, Becker JL, Sharipol A, Khan A, Schafer XL, Li Z, Streeter AR, Becker MW, Munger JC, Frisch BJ.   +10 more
europepmc   +1 more source

Infectious mononucleosis, other infections and prostate-specific antigen concentration as a marker of prostate involvement during infection [PDF]

, 2016
Aksoy, Alanen, Ascherio, Ayatollahi, Banez, Basch, Bergh, Berrington de Gonzalez, Borgermann, Bosch, Carter, Catalona, Chen, Elgamal, Fan, Fedewa, Grinstein, Hasui, Heidenreich, Joshi, Kadayifci, Kadayifci, Kilic, Krystyna, Kuller, Kutok, Lilja, Luzuriaga, Malavaud, Mandel, Moyer, Olsson, Oremek, Rickinson, Rubertone, Sfanos, Silverberg, Sindhwani, Smith, Stamey, Sutcliffe, Sutcliffe, Sutcliffe, Tchetgen, Whitaker, Whittemore, Wolf   +46 more
core   +2 more sources

Whole Exome Sequencing for Romanian Patients With Neurodevelopmental Disorders Through an International Collaboration

Clinical Genetics, EarlyView.
Whole exome sequencing for Romanian patients with neurodevelopmental disorders through an international collaboration—this study has provided a 50% diagnostic yield for patients with NDDs (27 positive results from 54 patients), supporting the implementation of a WES analysis that can identify SNVs, small INDELs, CNVs, and mitochondrial variants ...
Alexandru Caramizaru, Cristina Durac, Andreea Dumitrescu, Alexandru Calota‐Dobrescu, Alix de Becdelièvre, Marina Konyukh, Denise Cassandrini, Hane Lee, Go Hun Seo, Seung Woo Ryu, Mihai Cucu, Iuliana Manuela Dragomir, Andreea Catana, Homa Tajsharghi, Edoardo Malfatti, Florin Burada, Amelia Dobrescu   +16 more
wiley   +1 more source