Results 61 to 70 of about 58,003 (251)

Comparison of CD8+ T Cell Accumulation in the Brain During Human and Murine Cerebral Malaria

Frontiers in Immunology, 2019
CD8+ T cells have been shown to play a critical role in the pathogenesis of experimental cerebral malaria (ECM) in mice, but their role in development of human cerebral malaria (HCM) remains unclear.
Valentina Barrera, Michael J. Haley, Patrick Strangward, Elizabeth Attree, Steve Kamiza, Karl B. Seydel, Karl B. Seydel, Terrie E. Taylor, Terrie E. Taylor, Danny A. Milner, Alister G. Craig, Kevin N. Couper   +11 more
doaj   +1 more source

Reward Processing in Binge Eating and Harmful Drinking: A Systematic Review

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Binge eating and harmful drinking commonly co‐occur, which worsens the physical and psychological consequences associated with either behavior alone. Reward processing alterations have been demonstrated among individuals who engage in binge eating or harmful drinking alone; however, there is limited understanding of how different ...
Taylor N. Breddy, Kendall M. Schmidt, Lindsay P. Bodell   +2 more
wiley   +1 more source

Are Vegetarian and Vegan Diets Associated With Eating Disorder Symptoms? A Systematic Review and Meta‐Analysis

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective To synthesize the evidence on the associations between vegetarian and vegan diets (VVDs) and eating disorder (ED) symptoms compared with omnivorous diets across the lifespan. Method Following the preferred reporting items for systematic reviews and meta‐analyses (PRISMA) 2020 Guidelines, we searched PubMed, Scopus, Cochrane Library ...
Valentina Díaz‐Goñi, Arthur Eumann Mesas, Estela Jiménez‐López, Tomás Olivo‐Martins‐de‐Passos, Fernando Peral‐Martínez, Ana María Peraile‐Huerta, María Eugenia Visier‐Alfonso, Miriam Garrido‐Miguel, Bruno Bizzozero‐Peroni   +8 more
wiley   +1 more source

Restrict for Health or for Thinness? Liking but Not Approach Bias Differentiates Orthorexic Eating Behavior From Anorexia Nervosa in Responses to High‐Caloric Healthy vs. High‐Caloric Unhealthy Foods

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Individuals with high levels of orthorexic eating behavior (OEB) show a (pathological) fixation on healthy eating. Shared characteristics of OEB with individuals with anorexia nervosa (AN) raised debate over whether orthorexia nervosa constitutes a distinct disorder. Distinctions may lie in preference for and approach behavior toward
Hannah van Alebeek, Mareike Röttger, Jana Strahler, Katharina Eichin, Isabella Forwick, Jens Blechert, Ulrich Voderholzer, Julia Reichenberger   +7 more
wiley   +1 more source

Intramuscular blood flow in Duchenne and Becker Muscular Dystrophy: Quantitative power Doppler sonography relates to disease severity

Clinical Neurophysiology, 2020
Absent or truncated dystrophin in Duchenne (DMD) and Becker (BMD) muscular dystrophies results in impaired vasodilatory pathways and exercise induced muscle ischemia. Here, we used power Doppler sonography to quantify changes in intramuscular blood flow immediately following exercise in boys with D/BMD.We quantified changes in intramuscular blood flow ...
Alexander R, Dietz, Anne, Connolly, Amir, Dori, Craig M, Zaidman   +3 more
openaire   +3 more sources

Neighborhood Disadvantage and Comorbid Mental Health Conditions in Adolescents and Young Adults With Eating Disorders

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Anxiety and depression are highly prevalent among adolescents and young adults with eating disorders. A comorbid mental health condition is associated with worsened long‐term eating disorder outcomes. While individual risk factors for comorbid anxiety or depression and eating disorders have been elucidated, the impact of external ...
Anita V. Chaphekar, Qing Duan, Janet Zahner, Andrew F. Beck   +3 more
wiley   +1 more source

Pyruvate dehydrogenase autoantibodies in autoantibody‐negative patients with seizures are associated with reduced pyruvate dehydrogenase activity

Epilepsia, EarlyView.
Abstract Objective We investigated the presence and potential functional relevance of antimitochondrial autoantibodies in patients suspicious for autoimmune encephalitis (AIE) associated with psychiatric symptoms and/or seizures, who were negative for known antineuronal autoantibodies.
Annika Breuer, Chiara A. Hummel, Tobias Baumgartner, Juliane L. Berns, Afaf Milad Said, Isabel Bünger, Susanne Schoch, Gábor Zsurka, Harald Prüss, Wolfram S. Kunz, Rainer Surges, Albert J. Becker, Julika Pitsch   +12 more
wiley   +1 more source

Oligogenic inheritance in epilepsy: A systematic exome‐wide analysis

Epilepsia, EarlyView.
Abstract Objective Genetic factors contribute to the majority of epilepsies, but the exact genetic cause remains unknown in most patients. Incomplete penetrance and variable expressivity are frequent, and recent studies showed a burden of deleterious variants in epilepsy genes, suggesting a role for oligogenic inheritance.
Sarah Duerinckx, Barbara Gravel, Julie Soblet, Benjamin Legros, Susana Ferrao Santos, Wim Van Paesschen, Estelle Rikir, Epi25 Collaborative, Siwei Chen, Zaid Afawi, Quratulain Zulfiqar Ali, Danielle M. Andrade, Mutluay Arslan, Simona Balestrini, Carmen Barba, Tobias Baumgartner, Betül Baykan, Nerses Bebek, Felicitas Becker, Caitlin A. Bennett, Ahmad Beydoun, Francesca Bisulli, Christian Bosselmann, S. Hande Caglayan, Laura Canafoglia, Barbara Castellotti, Francine Chassoux, I‐Jun Chou, Seo‐Kyung Chung, Patrick Cossette, Chantal Depondt, Orrin Devinsky, Dennis J. Dlugos, Viola Doccini, Colin A. Ellis, Thomas N. Ferraro, Lorenzo Ferri, Mark Fitzgerald, Francesco Fortunato, Elena Freri, Tania Giangregorio, Tracy A. Glauser, Aslı Gundogdu‐Eken, Namrata Gupta, Kevin Haas, Erin L. Heinzen, Christian Hengsbach, Olivia Hoeper, Michele Iacomino, Yushi Inoue, Lara Jehi, Symon M. Kariuki, Karl Martin Klein, Susanne Knake, Andreas Koupparis, Ioanna Kousiappa, Roland Krause, Martin Krenn, Heinz Krestel, Wolfram S. Kunz, Austin Lacey, Stephan Lauxmann, Stephanie L. Leech, Gaetan Lesca, David Lewis‐Smith, Calwing Liao, Laura Licchetta, Kuang‐Lin Lin, Tarja Linnankivi, Daniel H. Lowenstein, Colin H.T. Lui, Ida Manna, Paula Marques, Patrick May, Davide Mei, RaAaella Minardi, Barbara Mostacci, Lorenzo Muccioli, Bernd A. Neubauer, Terence J. O'Brien, Savvas S. Papacostas, Elena Parrini, Manuela Pendziwiat, Francesca Ragona, Mark I. Rees, Antonella Riva, Philippe Ryvlin, Andrea Salmon, Ilaria Sammarra, Marcello Scala, Ingrid E. ScheAer, Susanne Schubert‐Bast, Paolo Scudieri, Graeme J. Sills, Sanjay M. Sisodiya, Hannah Stamberger, Ulrich Stephani, Carlotta Stipa, Pasquale Striano, Adam Strzelczyk, Rainer Surges, Toshimitsu Suzuki, Mariagrazia Talarico, George A. Tanteles, Marian Todaro, Meng‐Han Tsai, Birute Tumiene, Dilsad Turkdogan, Luc Valton, Andreas van Baalen, Annalisa Vetro, Yvonne G. Weber, Sarah Weckhuysen, Peter Widdess‐Walsh, Samuel Wiebe, Randi von Wrede, Kazuhiro Yamakawa, Zuhal Yapıcı, Fritz Zimprich, Milena Zizovic, Gábor Zsurka, Benjamin M. Neale, Samuel F. Berkovic, Solve‐RD DITF‐EpiCARE, Marc Abramowicz, Nicholas Allen, Simona Balestrini, Tobias Bartolomaeus, Ravishankara Bellampalli, Katherine Benson, Francesca Bisulli, Christian Boßelmann, Susan Byrne, Laura Canafoglia, Evelina Carapancea, Barbara Castellotti, Gianpiero Cavalleri, Roberta Cilio, Norman Delanty, Christel Depienne, Chantal Depondt, Sarah Duerinckx, Zakaria Eddafir, Kornelia Ellwanger, Silvana Franceschetti, Elena Freri, Hamidah Ghani, Tiziana Granata, Marie Greally, Renzo Guerrini, Tobias B. Haack, Eva Hammar Bouveret, Michele Iacomino, Rami Jamra, Josua Kegele, Christian Korff, Roland Krause, Alma Küchler, Robert Lauerer‐Braun, Damien Lederer, Elsa Leitão, Holger Lerche, Gaëtan Lesca, David Lewis‐Smith, Laura Licchetta, Frédéric Masclaux, Patrick May, Davide Mei, Cyril Mignot, Charissa Millevert, Raffaella Minardi, Patrick Moloney, Hiltrud Muhle, Mary O. Reghan, Joohyun Park, Elena Parrini, Manuela Pendziwiat, Konrad Platzner, Johanna Pohl, Mary Sandrine, Marcello Scala, Sanjay Sisodiya, Noor Smal, Hannah Stamberger, Pasquale Striano, Roxane van Heurck, Christina Vosseler‐Wolf, David Webb, Sarah Weckhuysen, Federico Zara, Alec Aeby, Guillaume Smits, Chantal Depondt   +192 more
wiley   +1 more source

Until programmed death do us tolerant

The Journal of Clinical Investigation, 2022
Healthy individuals are generally immunologically tolerant to proteins derived from one’s self (termed self proteins). However, patients with monogenic clotting disorders, like hemophilia A (HemA), lack central tolerance to the absent self protein. Thus,
David W. Scott
doaj   +1 more source

Arterial Perivascular Space‐Mediated Solute Transport in the Mouse Brain

Exploration, EarlyView.
The mechanisms underlying solute clearance from the brain parenchyma remain debated, with competing hypotheses involving bulk cerebrospinal fluid flow versus perivascular transport. Using multimodal in vivo imaging and computational modeling in mice, this study demonstrates that arterial pulsation drives bidirectional solute movement within the ...
Shiyong Li, Ye Wang, Guangyu Jia, Yamei Yu, Zhe Zhang, Qi Wang, Kaelyn V. Becker, Jonathan W. Engle, Dawei Jiang, Weibo Cai   +9 more
wiley   +1 more source