Results 51 to 60 of about 409,422 (304)
Vamorolone improves Becker muscular dystrophy and increases dystrophin protein in bmx model mice
iScience, 2023 Summary: There is no approved therapy for Becker muscular dystrophy (BMD), a genetic muscle disease caused by in-frame dystrophin deletions. We previously developed the dissociative corticosteroid vamorolone for treatment of the allelic, dystrophin-null ...
Nikki M. McCormack +5 more
doaj +1 more source
Agribusiness, EarlyView.ABSTRACT Market‐based solutions are increasingly tested to address aflatoxin issues in peanuts in developing countries. Although previous studies have found that Haitian grocery store shoppers are willing to pay a 21% premium for peanut butter with levels of aflatoxin that meet international standards, no information is available for the much larger ...
Phendy Jacques +2 more
wiley +1 more source
Breast Reconstruction in Becker Nevus Syndrome
Plastic and Reconstructive Surgery, Global OpenSummary:. Becker nevus syndrome is a rare cutaneous disorder characterized by the presence of a hyperpigmented patch of skin typically occurring on the upper trunk, often associated with hypertrichosis, and sometimes associated with musculoskeletal ...
Alexis K. Schlosser, MD +2 more
doaj +1 more source
Exonization of a deep intronic long interspersed nuclear element in Becker muscular dystrophy
Frontiers in Genetics, 2022 The precise identification of pathogenic DMD variants is sometimes rather difficult, mainly due to complex structural variants (SVs) and deep intronic splice-altering variants.
Zhiying Xie +12 more
doaj +1 more source
American Journal of Agricultural Economics, EarlyView.Abstract This study develops and empirically estimates a structural framework to decompose the causal pathways of multilevel behavioral interventions targeting adolescent health behaviors. We apply this framework to the Kids SIPsmartER (KSS) program, a 6‐month, school‐based intervention evaluated through a clustered randomized controlled trial in rural
Naveen Abedin +5 more
wiley +1 more source
, 2023 The BIND project is a EU-funded project that attempts to improve the characterisation of brain involvement in Duchenne and Becker Muscular Dystrophies (DMD and BMD). Here, we present our ongoing work on making multimodal data FAIR, the semantic models, and discuss challenges and opportunities based on our FAIRification experience.
Perdomo Quinteiro, Pablo +5 more
openaire +2 more sources
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.ABSTRACT In epidemiological studies, obsessive‐compulsive disorder (OCD) is robustly associated with increased risk of cardiometabolic disorders, including cardiovascular diseases, type 2 diabetes, and obesity. However, the mechanisms behind these associations are unclear. We conducted genetic correlation analyses to explore shared genetic etiology and
Robyn E. Wootton +217 more
wiley +1 more source
The Anatomical Record, EarlyView.Abstract To solidify their power over society, totalitarian regimes will usually eliminate any dissent, any perceived threats early on. These threats include not only political enemies but also educated and independent segments of society, such as professional associations.
Michael Hortsch
wiley +1 more source
Givinostat for Becker muscular dystrophy: A randomized, placebo-controlled, double-blind study
Frontiers in Neurology, 2023 ObjectiveNo treatments are approved for Becker muscular dystrophy (BMD). This study investigated the efficacy and safety of givinostat, a histone deacetylase pan-inhibitor, in adults with BMD.MethodsMales aged 18–65 years with a diagnosis of BMD ...
Giacomo P. Comi +18 more
doaj +1 more source
Skeletal pathologies in extant crocodilians as a window into the paleopathology of fossil archosaurs
The Anatomical Record, EarlyView.Abstract Crocodilians, together with birds, are the only extant relatives to many extinct archosaur groups, making them highly important for interpreting paleopathological conditions in a phylogenetic disease bracketing model. Despite this, comprehensive data on osteopathologies in crocodilians remain scarce.
Alexis Cornille +6 more
wiley +1 more source