Results 161 to 170 of about 971,040 (266)

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Beyond pathogen-specific preparedness: adaptable laboratory systems for emerging infections. [PDF]

Lancet Reg Health Eur
Sánchez-Seco MP, Palacios G.
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Special Issue "Human Traits and Genomics: An Integrative Perspective". [PDF]

Int J Mol Sci
Saccone S, Larizza L, Malerba G.
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Life as a Power of Deterritorialization (Desiring- -production and Living Labor I – Deleuze and Guattari) [PDF]

Praktyka Teoretyczna, 2011
Joanna Bednarek
doaj  

Cognitive sovereignty and neuro-justice: neurotechnological advancements and mental autonomy in the Global South. [PDF]

Front Public Health
Saracini C.
europepmc   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Institutional Special Needs Plans and End-of-Life Outcomes for Nursing Home Residents With Dementia.

JAMA Health Forum
White EM, Gozalo PL, Santostefano CM, Kosar CM, McGarry BE, Geng F, Zorowitz R, Grabowski DC, Mor V, Rahman M.   +9 more
europepmc   +1 more source

The doing, being, becoming, and belonging (DB3) scale: Development and initial content validity in an Australian context. [PDF]

Aust Occup Ther J
Hitch D, Pepin G.
europepmc   +1 more source