Results 41 to 50 of about 501,373 (309)

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

The Effect of Hydraulic Partitioning on Prediction the Rate of Bed Load Transport in Gravel-bed Rivers using Support Vector Machine [PDF]

open access: yesجغرافیا و پایداری محیط, 2019
Evaluation and prediction of sediment transport and associated processes have been one of the main issues of hydraulic and river engineers. There are some variables which affect the amount of bed load of a stream or river which may carry such as ...
Kiyoumars Roushangar   +2 more
doaj  

Estimation of Sediment Transport Rate of Karun River (Iran) [PDF]

open access: yesJournal of Hydraulic Structures, 2016
Several types of sediment transport equations have been developed for estimation of the river sediment materials during the past decades. The estimated sediment from these equations is very different, especially when they applied for a specific river ...
Navideh Najafpour   +3 more
doaj   +1 more source

Flood flow characteristics and bed load transport in non-vegetated compound straight channels [PDF]

open access: yes, 2016
Floods are the most common natural disasters in Malaysia and have damaged structures, infrastructures, crops and even causes fatalities. It may also lead to erosion and sedimentation in rivers and this will result to complex river behaviour.
Anuar, M. Z. T.   +7 more
core   +2 more sources

Blinatumomab Utilization in Pediatric B‐Cell Acute Lymphoblastic Leukemia: Experience From the Mountain West

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Blinatumomab is a bispecific T‐cell engager approved for the treatment of pediatric B‐cell acute lymphoblastic leukemia (B‐ALL). Outpatient home infusion reduces hospitalization burden and optimizes resource utilization, but is logistically challenging.
Angela Parra del Riego   +10 more
wiley   +1 more source

How Fast or How Many? Sources of Intermittent Sediment Transport

open access: yesGeophysical Research Letters, 2023
Near the threshold of grain motion, sediment transport is “on‐off” intermittent, characterized by large but rare bursts separated by long periods of low transport.
Santiago J. Benavides   +6 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

No-Deposition Sediment Transport in Sewers Using Gene Expression Programming [PDF]

open access: yesJournal of Soft Computing in Civil Engineering, 2017
The deposition of the flow of suspended particles has always been a problematic case in the process of flow transmission through sewers. Deposition of suspended materials decreases transmitting capacity.
Isa Ebtehaj, Hossein Bonakdari
doaj   +1 more source

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