Results 51 to 60 of about 3,969,409 (308)
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Advection and dispersion of bed load tracers
, 2017 . We use the erosion–deposition model introduced by Charru et al. ( 2004 ) to numerically simulate the evolution of a plume of bed load tracers entrained by a steady flow.
E. Lajeunesse, O. Devauchelle, F. James
semanticscholar +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Experimental Study of Bed Shear Stress in Straight Channels Covered with Dunes of Different Sizes [PDF]
علوم آب و خاک, 2023 The formation of bed form in alluvial rivers due to sediment transport has a significant effect on the hydraulic parameters of the flow such as bed shear stress.
M. Badzanchin +2 more
doaj
Influence of Bed Load and Suspended Load on Alternate Bar
PROCEEDINGS OF HYDRAULIC ENGINEERING, 1992 Hydraulic condition for alternate-bar formation in open channel flows with suspended sediment are determined by stability, analysis. It is shown that the condition for alternate bar formation in the flow with suspended sediment is much different from in the flow without suspended sediment.
Y. Watanabe, Tubino, Marco
openaire +2 more sources
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Optimal biocatalyst loading in a fixed bed
Journal of Industrial Microbiology & Biotechnology, 2007 The optimal distribution of biocatalyst in a fixed bed operating at steady state was determined to minimize the length of the bed for a fixed conversion of 95%. The distribution in terms of the biocatalyst loading on an inert support depends upon the axial distance from the bed entrance (continuous solution) as well as a set of dimensionless parameters
V, Tortoriello, G B, DeLancey
openaire +2 more sources
A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi +17 more
wiley +1 more source
Effect of bed load transport on the energy dissipation of step-pool system
Shui kexue jinzhan, 2017 Step-pool system is a typical bed micro-morphology in high gradient mountain rivers, which creates extremely high turbulence intensity and thus dissipates a majority the flow energy. The increase of the bed load transport intensity changed the flow field
LI Wenzhe, LI Zhiwei, WANG Zhaoyin
doaj +1 more source