Results 81 to 90 of about 5,611,372 (241)

VlPAG/DRN Microglia Drive Neuropathic Pain‐Induced Depression via a Defined Neuroimmune Axis

Advanced Science, EarlyView.
Peripheral nerve injury (SNI) induces neuropathic pain, activates midbrain microglia, and triggers an NLRP3–IL‐1β–dependent inflammatory cascade. IL‐1β signals through IL‐1R1 on vlPAG/DRN VGLUT2+ neurons (vlPAG/DRNGlu), inducing hyperexcitability and driving the vlPAG/DRNGlu→BNSTGABA circuit to produce the affective component of neuropathic pain ...
Jing Yang, Bing‐Jie Tang, Jia‐Yi Li, Shu‐Lan Xie, Shumin Duan, Junping Chen, Shengmei Zhu, Zhen‐Zhong Xu   +7 more
wiley   +1 more source

Modelling hospital and social care bed occupancy and use by elderly people in an English health district

, 2001
The paper confirms that exponential equations can be used to model the total system and sub-systems of institutional health and social care for elderly people using bed occupancy census data for 6068 elderly aged 65 and over.
Millard, P.H., McClean, S.I., Christodoulou, G., Jagger, C., Harrison, G.   +4 more
core   +1 more source

3D Printed Meter‐Scale Soft Origami Robots Capable of Load‐Bearing Actuation Via Crease Stiffness Modulation

Advanced Science, EarlyView.
Origami has inspired numerous soft deployable mechanisms for safe human‐robot interaction, while its intrinsic kinematic instability at arbitrary configurations limited their practical robotic application. This work presents a 3D printed meter‐scale origami robotic actuator capable of load‐bearing deformation through creaseline stiffness modulation.
Sung Yol Yu, Sang‐Joon Ahn, Wonchul Lee, Seunguk Moon, Hyun‐Jin Hong, Kyu‐Jin Cho   +5 more
wiley   +1 more source

Efficacy analysis using Pabon Lasso Model and comparing with national standards of educational hospitals affiliate to Qom University of Medical Sciences

بیمارستان, 2015
Background: The Pabon Lasso graphical Model is a method to determine hospital efficacy as one of the most important part of health system in developing countries.
Abolfazli Mohammadbeig, Zohreh Anbari, maryam hemmati, ahmad rahbar, narges mohammad salehi, fariba eslami moghaddam   +5 more
doaj  

Inpatient Capacity at Children’s Hospitals during Pandemic (H1N1) 2009 Outbreak, United States

Emerging Infectious Diseases, 2011
Quantifying how close hospitals came to exhausting capacity during the outbreak of pandemic influenza A (H1N1) 2009 can help the health care system plan for more virulent pandemics. This ecologic analysis used emergency department (ED) and inpatient data
Marion R. Sills, Matthew Hall, Evan S. Fieldston, Paul D. Hain, Harold K. Simon, Thomas V. Brogan, Daniel B. Fagbuyi, Michael B. Mundorff, Samir S. Shah   +8 more
doaj   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source

Organic Nanozyme‐Embedded Biotherapeutic Thermosensitive Hydrogel for Extracellular GSH Depletion and Postoperative Tumor Suppression

Advanced Science, EarlyView.
A temperature‐sensitive hydrogel loaded with cyanine nanozymes and Escherichia coli is locally injected into postoperative tumor resection beds. Upon light irradiation, synergistic PTT and PDT work with cascaded reactive oxygen species to deplete extracellular GSH, eliminate residual tumor cells, and induce robust antitumor immune responses for ...
Cong Jiang, Zifan Yang, Rong Guo, Meng Suo, Guowei Wang, Dong Chen, Lilin Su, Fuhuan Wang, Shipeng Ning, Kelong Fan, Xuan Wang   +10 more
wiley   +1 more source

Analysis of the patient occupancy rate (BOR), operational cost budget and activity ratio on financial performance based on income capability of PNBP covering operational cost of public service agency (BLU) of DKI Jakarta provincial hospital.

Jurnal Ilmiah Wahana Akuntansi, 2017
The purpose of this research is to know the influence of activity, operational cost budgeting, and bed occupancy rate on financial performance based on ability of (PNBP) revenue to cover operating cost public service agency hospital. This study aims to
Istiqomah Dwi Putri , Achmad Fauzi
doaj   +1 more source

Marketing Mix by Bed Occupancy Ratio (Bor) [PDF]

, 2013
Introduction: Bed Occupancy Ratio (BOR) in RSI Arafah Mojosari during the last three years are at under ideal rate and the lowest of the three existing hospitals in the area of Mojosari.
Muhith, A. (Abdul), Nursalam, N. (Nursalam), Saputra, M. H. (M)   +2 more
core  

Time-series analysis of the impact of bed occupancy rates on the incidence of methicillin-resistant staphylococcus aureus infection in overcrowded general wards [PDF]

, 2008
Objective. We investigated the impact of bed occupancy, particularly overcrowding, on the incidence of methicillin-resistant Staphylococcus aureus (MRSA) infection in general ward settings.Methods. We performed a time-series and mixed-model analysis of
Scicluna, Elizabeth, Borg, Michael Angelo, Suda, David   +2 more
core   +1 more source