Results 1 to 10 of about 152,455 (261)

Retinal venular vessel diameters are smaller during ten days of bed rest [PDF]

Scientific Reports, 2023
Older individuals experience cardiovascular dysfunction during extended bedridden hospital or care home stays. Bed rest is also used as a model to simulate accelerated vascular deconditioning occurring during spaceflight.
Adam Saloň, Göktuğ Mert Çiftci, Damir Zubac, Boštjan Šimunič, Rado Pišot, Marco Narici, Per Morten Fredriksen, Benedicta Ngwenchi Nkeh-Chungag, Harald Sourij, Omar Šerý, Karin Schmid-Zalaudek, Bianca Steuber, Patrick De Boever, Nandu Goswami   +13 more
doaj   +2 more sources

Initial Glutathione Depletion During Short-Term Bed Rest: Pinpointing Synthesis and Degradation Checkpoints in the γ-Glutamyl Cycle [PDF]

Antioxidants
Hypokinesia triggers oxidative stress and accelerates the turnover of the glutathione system via the γ-glutamyl cycle. Our study aimed to identify the regulatory checkpoints controlling intracellular glutathione levels.
Filippo Giorgio Di Girolamo, Filippo Mearelli, Mariella Sturma, Nicola Fiotti, Kaja Teraž, Alja Ivetac, Alessio Nunnari, Pierandrea Vinci, Boštjan Šimunič, Rado Pišot, Gianni Biolo   +10 more
doaj   +2 more sources

Changes in real-world walking speed following 60-day bed-rest [PDF]

npj Microgravity
The aim of this work was to explore whether real-world walking speed (RWS) would change as a consequence of 60-day bed-rest. The main hypothesis was that daily RWS would decrease after the bed-rest, with a subsequent recovery during the first days of re ...
Marcello Grassi, Fiona Von Der Straten, Charlotte Pearce, Jessica Lee, Marcin Mider, Uwe Mittag, Wolfram Sies, Edwin Mulder, Martin Daumer, Jörn Rittweger   +9 more
doaj   +2 more sources

Capillary rarefaction during bed rest is proportionally less than fibre atrophy and loss of oxidative capacity

Journal of Cachexia, Sarcopenia and Muscle, 2022
Background Muscle disuse from bed rest or spaceflight results in losses in muscle mass, strength and oxidative capacity. Capillary rarefaction may contribute to muscle atrophy and the reduction in oxidative capacity during bed rest.
Paul William Hendrickse, Rob C.I. Wüst, Bergita Ganse, Ifigeneia Giakoumaki, Jörn Rittweger, Alessandra Bosutti, Hans Degens   +6 more
doaj   +1 more source

The effect of short‐term exercise prehabilitation on skeletal muscle protein synthesis and atrophy during bed rest in older men

Journal of Cachexia, Sarcopenia and Muscle, 2021
Background Poor recovery from periods of disuse accelerates age‐related muscle loss, predisposing individuals to the development of secondary adverse health outcomes.
Benoit Smeuninx, Yasir S. Elhassan, Konstantinos N. Manolopoulos, Elizabeth Sapey, Alison B. Rushton, Sophie J. Edwards, Paul T. Morgan, Andrew Philp, Matthew S. Brook, Nima Gharahdaghi, Kenneth Smith, Philip J. Atherton, Leigh Breen   +12 more
doaj   +1 more source

The Aging Muscle in Experimental Bed Rest: A Systematic Review and Meta-Analysis

Frontiers in Nutrition, 2021
Background: Maintaining skeletal muscle mass and function in aging is crucial for preserving the quality of life and health. An experimental bed rest (BR) protocol is a suitable model to explore muscle decline on aging during inactivity.Objective: The ...
Filippo Giorgio Di Girolamo, Filippo Giorgio Di Girolamo, Nicola Fiotti, Zoran Milanović, Zoran Milanović, Zoran Milanović, Roberta Situlin, Filippo Mearelli, Pierandrea Vinci, Boštjan Šimunič, Rado Pišot, Marco Narici, Gianni Biolo   +12 more
doaj   +1 more source

Effects of head-down bed rest on the executive functions and emotional response. [PDF]

PLoS ONE, 2012
Prolonged bed rest may cause changes in the autonomic nervous system that are related to cognition and emotion. This study adopted an emotional flanker task to evaluate the effect of 45 days -6° head-down bed rest (HDBR) on executive functioning in 16 ...
Qing Liu, Renlai Zhou, Shanguang Chen, Cheng Tan   +3 more
doaj   +1 more source

Adult Female Sleep During Hypoxic Bed Rest

Frontiers in Neuroscience, 2022
PurposeHypobaric hypoxic habitats are currently being touted as a potential solution to minimise decompression procedures in preparation for extra vehicular activities during future space missions.
Jeroen Van Cutsem, Jeroen Van Cutsem, Nathalie Pattyn, Nathalie Pattyn, Olivier Mairesse, Olivier Mairesse, Bérénice Delwiche, Bérénice Delwiche, Helio Fernandez Tellez, Martine Van Puyvelde, Martine Van Puyvelde, Martine Van Puyvelde, Emilie Lacroix, Adam C. McDonnell, Ola Eiken, Igor B. Mekjavic, Igor B. Mekjavic   +16 more
doaj   +1 more source

Mechanical deconditioning of the heart due to long-term bed rest as observed on seismocardiogram morphology

npj Microgravity, 2022
During head-down tilt bed rest (HDT) the cardiovascular system is subject to headward fluid shifts. The fluid shift phenomenon is analogous to weightlessness experienced during spaceflight microgravity.
Bradley Hoffmann, Parastoo Dehkordi, Farzad Khosrow-Khavar, Nandu Goswami, Andrew P. Blaber, Kouhyar Tavakolian   +5 more
doaj   +1 more source

Inter-Person Differences in Isometric Coactivations of Triceps Surae and Tibialis Anterior Decrease in Young, but Not in Older Adults After 14 Days of Bed Rest

Frontiers in Physiology, 2022
We examined activation patterns of the gastrocnemius medialis (GM), gastrocnemius lateralis (GL), soleus (SO), and tibialis anterior (TA) muscles in eight older (58.4 ± 3.3 years) and seven young (23.1 ± 2.9 years) participants, before and after 14 days ...
Matjaž Divjak, Gašper Sedej, Nina Murks, Mitja Gerževič, Mitja Gerževič, Uros Marusic, Uros Marusic, Rado Pišot, Boštjan Šimunič, Aleš Holobar   +9 more
doaj   +1 more source