Results 31 to 40 of about 155,817 (261)

Implications of Bed Rest for Patients with Acute Deep Vein Thrombosis: A Qualitative Study

Patient Preference and Adherence, 2020
Jian-Mei Gong,1 Jian-Shi Du1,2 ,* Dong-Mei Han2, * 1Nursing School of Jilin University, Changchun City, Jilin Province, People’s Republic of China; 2Department of the Lymphatic and Vascular Surgery, China-Japan Union Hospital of Jilin University ...
Gong JM, Du JS, Han DM
doaj  

The effect of bed rest after intrauterine insemination on pregnancy outcome

Middle East Fertility Society Journal, 2015
Objective: To compare the effect of bed rest after intrauterine insemination for 5, 10 and 20 mins on the pregnancy rate. Design: Randomized controlled trial. Setting: Integrated Fertility Center and Agial Fertility Center.
Yasser Ibrahim Orief, Ahmed Samy El-agwany, Emad Abd Elmoneem Darwish, Noha Mustafa Salim   +3 more
doaj   +1 more source

Bedrest, frailty and exercise countermeasures: A 14-day head-down tilt study in mid-older aged adults

Experimental Gerontology
Background: Physical inactivity, particularly bed rest during hospitalisation, has adverse effects on frailty. Head-down tilt bed rest paradigms have been used as models of accelerated aging.
Joanna M. Blodgett, Judith Godin, D. Scott Kehler, Susan E. Howlett, Kenneth Rockwood, Olga Theou   +5 more
doaj   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

A Technique of Forced Expiratory Noise Time Evaluation Provides Distinguishing Human Pulmonary Ventilation Dynamics During Long-Term Head-Down and Head-Up Tilt Bed Rest Tests Simulating Micro and Lunar Gravity

Frontiers in Physiology, 2018
Estimating the effect of microgravity/hypogravity on pulmonary ventilation function remains topical. Recently developed acoustic techniques based on the evaluation of the forced expiratory noise time (FETa) were hypothesized to be a promising tool for ...
Veronika V. Malaeva, Vladimir I. Korenbaum, Irina A. Pochekutova, Anatoly E. Kostiv, Svetlana N. Shin, Vladimir P. Katuntsev, Viktor M. Baranov   +6 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Gluteal Muscle Atrophy and Increased Intramuscular Lipid Concentration Are Not Mitigated by Daily Artificial Gravity Following 60-Day Head-Down Tilt Bed Rest

Frontiers in Physiology, 2021
Exposure to spaceflight and head-down tilt (HDT) bed rest leads to decreases in the mass of the gluteal muscle. Preliminary results have suggested that interventions, such as artificial gravity (AG), can partially mitigate some of the physiological ...
Vienna Tran, Enrico De Martino, Julie Hides, Gordon Cable, Gordon Cable, James M. Elliott, James M. Elliott, Mark Hoggarth, Mark Hoggarth, Jochen Zange, Kirsty Lindsay, Dorothée Debuse, Andrew Winnard, David Beard, Jonathan A. Cook, Jonathan A. Cook, Sauro E. Salomoni, Tobias Weber, Tobias Weber, Jonathan Scott, Jonathan Scott, Paul W. Hodges, Nick Caplan   +22 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

The Physiology Associated With “Bed Rest” and Inactivity and How It May Relate to the Veterinary Patient With Spinal Cord Injury and Physical Rehabilitation

Frontiers in Veterinary Science, 2021
In the twentieth century, bed rest was commonly prescribed by human healthcare professionals as a treatment for a variety of ailments including spinal cord injury and disease.
Stephanie A. Thomovsky
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source