Effects of 60 days of 6° head-down bed rest on the composition and function of the human gut microbiota. [PDF]
Li Y+14 more
europepmc +1 more source
A 3D bioprinted HNSCC model for use in anti‐cancer drug testing is established in proof‐of‐concept. The innovative tunicate‐derived nanocellulose hydrogel proved to be a viable alternative to gelatin‐based hydrogel, offering improved bioprintability for HNSCC model establishment.
Alexya Azhakesan+7 more
wiley +1 more source
Simulating microgravity with 60 days of 6 degree head-down tilt bed rest compromises sleep. [PDF]
Strauch L+6 more
europepmc +1 more source
Deterioration of Left Ventricular Chamber Performance After Bed Rest
Merja Perhonen+2 more
openalex +1 more source
Lipid Nanoparticle‐Mediated CRISPR‐Cas13a Delivery for the Control of Bacterial Infection
New formulations of lipid nanoparticles (LNPs) that can deliver nucleic acids to Gram‐negative bacteria are proposed to combat bacterial infection. The delivery of nucleic acids by LNPs is aided by LNP‐helpers which weaken the bacterial outer membrane. LNPs encapsulating the Cas13a/gRNA expression vector achieve an antibacterial effect in both in vivo ...
Bookun Kim+9 more
wiley +1 more source
Physical and Psychological Burden of Bed Rest on Patients Following Free Flap Reconstruction of the Lower Limb: A Systematic Review and Possible Solutions. [PDF]
Dietrich LG, Zubler C.
europepmc +1 more source
Elevated biomarkers of neural injury in older adults following head-down bed rest: links to cardio-postural deconditioning with spaceflight and aging. [PDF]
Blaber AP+3 more
europepmc +1 more source
Most in vitro cancer models lack cellular diversity, functional complexity, and clinical relevance. This work highlights the generation of an innovative dynamic tetraculture with autologous patient‐derived cells within a vascularized tumor‐on‐chip, as well as the recapitulation of endothelial anergy features induced by the tumor microenvironment ...
Christine Lansche+16 more
wiley +1 more source
Mechanical countermeasures for spaceflight-associated neuro-ocular syndrome during 30-days of head down tilt bed rest: design, implementation, and tolerability. [PDF]
Moestl S+20 more
europepmc +1 more source
Modulation of vestibular input by short-term head-down bed rest affects somatosensory perception: implications for space missions. [PDF]
Gammeri R+9 more
europepmc +1 more source