Results 21 to 30 of about 10,977 (167)

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte   +11 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Microbial production of succinic acid using crude and purified glycerol from a Crotalaria juncea based biorefinery

Biotechnology Reports, 2016
Microbial conversion of crude and purified glycerol obtained in the process of biorefining Crotalaria juncea is carried out to produce succinic acid using Escherichia coli.
Suvra Sadhukhan, Raffaella Villa, Ujjaini Sarkar   +2 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Place attachment and attitudes to landscape change for tree planting and net zero

People and Nature
To reach net zero by 2050 the Paris Agreement on Climate Change recommended tree cover expansion and tree planting to support Nationally Determined Contributions. We use place attachment in the context of historical events to explore landscape change and
Sheena Carlisle, Susan Baker, Euan Bowditch, Natasha Constant, Tom Finch, Melissa Minter, Alix Syder   +6 more
doaj   +1 more source

Biostratigraphic Interpretation of Lutut Beds, Kerek Formation, Based on Foraminifera Fossils

JGEET: Journal of Geoscience, Engineering, Environment and Technology, 2023
Lutut Beds are the sandstone beds exposed in the northwest margin of Kendeng Basin, which contain abundant metamorphic-quartz grains, frequent recycled sedimentary quartz, and reworked bioclasts.
Anis Kurniasih, Ikhwannur Adha, Hasnan Lutfi Dalimunthe, Reddy Setyawan, Wahyu Budhi Khorniawan, Nurakhmi Qadaryati, Anita Galih Ringga Jayanti, Fadyaz Pugu Wijaya   +7 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Equity in distribution of hospital beds in Iran [PDF]

مجله علمی دانشگاه علوم پزشکی کردستان, 2020
Background and Aim: Equitable distribution of health system resources and hospital beds is crucial for an acceptable level of health for all the people of the country.
Ali mohammad Mosadeghrad, Ghasem Janbabaei, Behzad Kalantari, Alireza Darrudi, Hamed Dehnavi   +4 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Flow Studies using Laser Anemometry Technique in a Small Power Unit Radial Inflow Turbine

International Journal of Rotating Machinery, 1997
T-100 is a multipurpose small power unit developed by Sundstrand Power Systems (USA). An extensive research programme was launched for the detailed tests of the rig components including inlet protection system, Compressor stage, Combustor and the Turbine
Sohail H. Zaidi, Robin L. Elder
doaj   +1 more source