Results 31 to 40 of about 226,557 (265)
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola +4 more
wiley +1 more source
Flow Studies using Laser Anemometry Technique in a Small Power Unit Radial Inflow Turbine
T-100 is a multipurpose small power unit developed by Sundstrand Power Systems (USA). An extensive research programme was launched for the detailed tests of the rig components including inlet protection system, Compressor stage, Combustor and the Turbine
Sohail H. Zaidi, Robin L. Elder
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
FEATURES OF THE INFRASTRUCTURE AND FLOWS INVOLVED IN TOURISM DEVELOPMENT IN MUREŞ COUNTY [PDF]
Tackling the topic regarding the spatial distribution of the accommodation/lodging infrastructure of Mureş County for the entire transition period required first and foremost a quantitative analysis, with data sets from the National Institute of ...
George-Bogdan TOFAN, Adrian NIŢĂ
doaj
Upper and lower plane bed definitions revised
Sedimentary structures in ancient deposits are clues to reconstruct past geohazards. While parallel lamination formed by plane beds is one of the most common sedimentary structures in event deposits such as turbidites, the formative conditions for plane ...
Koji Ohata +2 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Assessing equity in the distribution of hospital beds: evidence from northern Iran
Objective: To assess equity in the distribution of hospital beds in northern Iran. Methods: In this cross-sectional study, we investigated the degree of equity by using 2016 census data from 16 cities in Guilan province.
Javad Ebrahimzadeh +7 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source

