Results 191 to 200 of about 173,687 (308)

Sequential, chromosome‐specific glutamine synthetase double knockout with Cas‐CLOVER establishes enhanced CHO platforms for cell line development

open access: yesBiotechnology Progress, EarlyView.
This study established the first creation of a commercially available double GS knockout (DKO) from a single KO in CHO‐K1 cells, called CleanCut GS CHO using Cas‐CLOVER. When combined with the Harbor‐IN transposase system, CleanCut GS CHO cells demonstrated a highly antibody productivity.
Cintia Gomez Limia   +7 more
wiley   +1 more source

Voclosporin‐induced gingival enlargement: A case report

open access: yesClinical Advances in Periodontics, EarlyView.
Abstract Background Drug‐influenced gingival enlargement (DIGE) is a recognized adverse effect of certain medications, particularly immunosuppressants like cyclosporin and tacrolimus. However, there have been no documented cases of DIGE associated with voclosporin, a newer calcineurin inhibitor used primarily to treat lupus nephritis.
Francesca Racca   +2 more
wiley   +1 more source

Excessive Ostial Stent Protrusion: Evaluation of Management Strategies and Clinical Outcomes of the Side Flap Technique

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Backgrounds Accurate stent positioning in aorto‐ostial lesions remains challenging due to complex three‐dimensional anatomy, lack of optimal fluoroscopic projections, and high rates of geographic miss. Stent overhang impairs guide catheter re‐engagement and complicates future revascularization.
Gregor Leibundgut   +7 more
wiley   +1 more source

Mini‐Hairpin DNA: Extraordinarily Stable Structure and Its Applications

open access: yesChemistry – A European Journal, EarlyView.
Mini‐hairpin DNA fragments containing GCGAAGC and GCGAAAGC form exceptionally stable hairpin‐like structures, with only two G−C pairs and one sheared G−A pair, remaining undenatured in 7 M urea and resisting nuclease digestion. These mini‐hairpin sequences frequently appear in replication and transcription origins, influence DNA sequencing fidelity ...
Michiko Kimoto, Ichiro Hirao
wiley   +1 more source

High‐Temperature Heat Pump Test Bench with n‐Butane (R‐600) Generating Steam

open access: yesChemie Ingenieur Technik, EarlyView.
This work involves building a test bench for a high‐temperature heat pump (HTHP) and analyzing the measurements. The focus is on steam generation using an HTHP to decarbonize process steam demand. The findings indicate that stable steam generation is possible, providing a higher heat transfer coefficient in the heat pump's condenser.
Sebastian Benkert   +7 more
wiley   +1 more source

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