Results 31 to 40 of about 4,851,513 (185)

Behçet's disease: Successful treatment with infliximab in 7 patients with severe vascular manifestations - a retrospective analysis

, 2012
To evaluate the therapeutic effect of infliximab in patients with inflammatory vascular lesions due to Behçet's disease (BD)
Iris Baumgartner, Sabine Adler, Peter M. Villiger, Baumgartner, Iris, Villiger, Peter M, Adler, Sabine   +5 more
core   +1 more source

Case report: A case of neuro-Behçet's syndrome presenting as brain stem mass lesions

Frontiers in Neurology, 2023
Neuro-Behçet's syndrome, a severe and rare manifestation of Behçet's disease (BD), can be misdiagnosed due to its challenging clinical presentation.
Folusakin Ayoade, Salma Hernandez, Nadine Montreuil, Katherine Drews-Elger, Katherine Drews-Elger, Tanya Quiroz, Candice A. Sternberg   +6 more
doaj   +1 more source

Colonoscopic findings in intestinal Behçet's disease

, 2001
The aims of this study were to investigate the clinical and colonoscopic characteristics of patients with intestinal Behçet's disease and to compare the findings of typical and atypical intestinal Behçet's disease.
방동식, 김원호
core   +1 more source

An Aggregation‐Induced Polymerization Poly(Disulfide)‐Drug Nanoplatform for Autoimmune Uveitis Therapy via Inhibiting the cGAS‐STING Pathway

Advanced Science, EarlyView.
A cationic poly(disulfide)‐drug nanoplatform (LA/DexP) was developed to treat experimental autoimmune uveitis (EAU). With potent blood‐retinal barrier penetrability, LA/DexP releases DSP in response to high ROS and scavenges cfDNA to inhibit the cGAS‐STING signaling pathway.
Yuelan Wu, Wenbo Geng, Qinjin Dai, Wanyun Zhang, Yuxian Lai, Pei Zhang, Chunjiang Zhou, Yinuo Wang, Qingfeng Cao, Xiang Luo, Yujie Lai, Changwei Huang, Peizeng Yang   +12 more
wiley   +1 more source

BehÇet's disease: a rheumatologic perspective

, 1997
Behçet's disease is recognized as a multisystemic disease with various organ involvement including skin, mucous membrane, eyes, joints, veins, arteries, gastrointestinal tract, meninges, and brain.
이수곤
core   +1 more source

A Rare De Novo Missense Mutation in IFT122 Confers a Genetic Susceptibility Factor of Idiopathic Pediatric Uveitis Via Trio‐based Whole‐Exome Sequencing

Advanced Science, EarlyView.
A rare de novo IFT122‐A773E variant is identified in idiopathic pediatric uveitis and shown to exacerbate retinal inflammation and barrier dysfunction. Mechanistically, the variant enhances IFT43 interaction, elevates calcium signaling, and activates the MEK/ERK/FRA1 axis, revealing a previously unrecognized cilia‐associated pathway that may increase ...
Qian Zhou, Jiaxing Huang, Yilin Wang, Xingran Li, Xianyang Liu, Lingyu Dai, Hongshun Li, Qingfeng Wang, Jiangyi Liu, Guannan Su, Wanyun Zhang, Yang Deng, Qingfeng Cao, Yujie Lai, Xiang Luo, Changwei Huang, Ling Chen, Shengping Hou, Peizeng Yang   +18 more
wiley   +1 more source

Upper Gastrointestinal Involvement in Behcet’s Disease

The Korean Journal of Gastroenterology
Background/Aims: Behcet's disease is an idiopathic, chronic, multisystemic vasculitis characterized by recurrent oral and genital ulcers, ophthalmologic inflammation, and skin lesions.
Hogyung Jun, Hyun Joo Song, Ji Hwan Mun, Heung Up Kim   +3 more
doaj   +1 more source

Antistreptolysin O Levels in Patients with Behcet’s Disease

Eurasian Journal of Medicine, 2019
Objective: Behcet’s disease is a multisystem inflammatory disorder, and its etiology has not been defined clearly yet. In this study, we aimed to investigate the antistreptolysin O (ASO) levels of patients with Behcet’s disease. Materials and Methods:
Hulya Uzkeser, Saliha Karatay, Kadir Yildirim, Ali Karakuzu, Muhammed Hamidullah Uyanik   +4 more
doaj   +1 more source

Upadacitinib Restrains the Pathogenic Fitness of CD4+ T Cells and Aberrant B Cell Programming in Optic Neuritis

Advanced Science, EarlyView.
Single‐cell profiling and functional perturbation reveal coordinated JAK1‐pSTAT3 downstream programs in optic neuritis, including MCL1‐dependent fitness of pathogenic CD4+ Tem cells and glycolysis‐linked, cholesterol‐sensitive B‐cell responses associated with RORA. Upadacitinib disrupts this reciprocal T‐B‐cell circuit and alleviates neuroinflammation,
Gengchen Jiang, Qi Jiang, Lian Han, Yue Peng, Xingyu Liu, Tong Yang, Hao Huang, Jiaying Liu, Yuan Gao, Hui Yang, Wenjun Zou, Zhaohuai Li, Wenru Su   +12 more
wiley   +1 more source

The influence of pregnancy on BehÇet's disease

, 1997
BehÇet's disease is a multisystem disorder that affects mainly young adults. Conflicting reports of the effects of pregnancy on the course of BehÇet's disease have been reported.
방동식
core   +1 more source