Results 51 to 60 of about 10,530,094 (182)

Lack of an association of PD-1 and its ligand genes with Behcet's disease in a Chinese Han population. [PDF]

PLoS ONE, 2011
BACKGROUND: Behcet's disease is a chronic, multi-systemic autoimmune disease. Programmed cell death 1 (PD-1) gene is one of non-human leucocyte antigen genes. It has been demonstrated to be associated with several autoimmune diseases. However, only a few
Qianli Meng, Haike Guo, Shengping Hou, Zhengxuan Jiang, Aize Kijlstra, Peizeng Yang   +5 more
doaj   +1 more source

Dense genotyping of immune-related loci implicates host responses to microbial exposure in Behçet’s disease susceptibility

Nature Genetics, 2017
We analyzed 1,900 Turkish Behçet's disease cases and 1,779 controls genotyped with the Immunochip. The most significantly associated SNP was rs1050502, a tag SNP for HLA-B*51.
M. Takeuchi, N. Mizuki, A. Meguro, M. Ombrello, Y. Kirino, Colleen L. Satorius, J. Le, M. Blake, B. Erer, T. Kawagoe, D. Ustek, İ. Tuğal-Tutkun, E. Seyahi, Y. Ozyazgan, I. Sousa, F. Davatchi, V. Francisco, F. Shahram, B. Abdollahi, A. Nadji, Niloofar Mojarad Shafiee, Fahmida Ghaderibarmi, S. Ohno, A. Ueda, Y. Ishigatsubo, M. Gadina, S. A. Oliveira, A. Gül, D. Kastner, E. Remmers   +29 more
semanticscholar   +1 more source

The genetic landscape of congenital diarrheas and very early onset inflammatory bowel disease in the Middle East

JPGN Reports, EarlyView.
Abstract Objectives Monogenic causes of congenital diarrheas and enteropathies (CoDE) and very early onset inflammatory bowel disease (VEOIBD) are mostly recessive and therefore more prevalent in populations with increased consanguinity rates. To assess the genetic basis of these disorders in a likely high‐prevalence population, we established a multi ...
Lily Gillette, Muna Al Safar, Ganeshwaran H. Mochida, Casey Johnson, Stephen Babcock, Klaus Schmitz‐Abe, Michael Field, Jessica Yang, Richelle Bearup, Ahmed Megahed, Mohammed Ezz El Regal Abbas, Tarek Baraket, Sherine Elziny, Ali Sobh, Gulin Eren, Fawaz AlRefaee, Rana Bitar, Mohamed Miqdady, Pankaj B. Agrawal, Scott B. Snapper, Jay R. Thiagarajah, Jodie Ouahed   +21 more
wiley   +1 more source

High levels of endothelial progenitor cells and circulating endothelial cells in patients with Behçet's disease and their relationship to disease activity [PDF]

Anais Brasileiros de Dermatologia, 2019
: Background: Behçet's disease is a multisystemic vasculitis, associated with vascular endothelial dysfunction. Currently, the prognosis is unpredictable, because there is still no valid laboratory marker indicating the disease activity in Behçet's ...
Deniz Aksu Arica, Burak Akşan, Asim Örem, Buket Akcan Altinkaynak, Savaş Yayli, Mehmet Sönmez   +5 more
doaj   +1 more source

Juvenile Gangrenous Vasculitis of the Scrotum or Scrotum Lipschütz Ulcers

JEADV Clinical Practice, EarlyView.
ABSTRACT Lipschütz genital ulcers are traditionally described in adolescent females and often linked to acute viral infections. Their male counterpart remains poorly characterised. We report a 59‐year‐old man with sudden onset of unilateral necrotic ulcers on the scrotum and inguinal region following a brief febrile episode and mild pharyngitis ...
Francesco Bellinato, Paolo Gisondi, Giampiero Girolomoni   +2 more
wiley   +1 more source

Triggering of Koebner Phenomenon by Picosecond Laser in a Psoriatic Patient: Clinical and Immunopathologic Insights

Lasers in Surgery and Medicine, EarlyView.
ABSTRACT Objectives To report the first case of Koebner phenomenon induced by picosecond laser treatment in a patient with psoriasis. We analyzed the clinical and histopathological features and discussed the possible mechanism by which the laser's photomechanical effect triggered the reaction.
Teppei Sakai, Koya Sonoda, Jun Omatsu
wiley   +1 more source

An Exploration of the Relationships Between Science Identity and Disabled Identities in Undergraduate Science Students

Science Education, EarlyView.
ABSTRACT Science identity is often conceptualized through constructs such as performance, competence, recognition, and interest, with prior research highlighting the roles of race, gender, and cultural background in shaping students' experiences. However, limited scholarship has examined how disability interacts with science identity in postsecondary ...
Ariel Chasen, Maura Borrego
wiley   +1 more source

Paradoxical Behçet’s Disease after Ixekizumab: A Case Report and Literature Review

Indian Journal of Dermatology
Behçet’s disease is a chronic inflammatory condition that affects multiple organs and systems. It is characterized by recurrent oral and genital ulcers.
Yue-Kang Ren, Ling Ren, Wen Sun, Hong-Ye Liu, Shu-Ping Guo   +4 more
doaj   +1 more source

A rare involvement in Behcet's Disease: Carotid artery aneurysm

İstanbul Kuzey Klinikleri, 2017
Behçet's disease is an inflammatory disease characterized by recurrent oral aphthous ulcers and various accompanying systemic pathologies. These additional pathologies include ocular and neurologic disease, genital ulcers, skin lesions, arthritis and ...
Hamit Serdar Başbuğ, Yalçın Günerhan, Hakan Göçer, Kanat Özışık   +3 more
doaj   +1 more source

Erythema nodosum in Behçet’s disease in remission: Think COVID-19?

SAGE Open Medical Case Reports, 2023
The coronavirus disease has several manifestations related to the activation of the immune system. Because of such activation, autoimmune diseases, including vasculitis, have been reported to occur.
Georges El Hasbani, Ali SM Jawad, Imad Uthman   +2 more
doaj   +1 more source