Results 111 to 120 of about 9,365,944 (369)

Experimental validation of in silico predicted RAD locus frequencies using genomic resources and short read data from a model marine mammal

open access: yesBMC Genomics, 2019
Background Restriction site-associated DNA sequencing (RADseq) has revolutionized the study of wild organisms by allowing cost-effective genotyping of thousands of loci.
David L. J. Vendrami   +2 more
doaj   +1 more source

The development of laboratory animal science and animal care of legislation and the consummation [PDF]

open access: yes, 2012
Laboratory animal science is the use of non-human animals in experiments to obtain new knowledge and new technologies in biomedical research and testing.
Shizhong, Zhou
core  

Rhythm and synchrony in animal movement and communication

open access: yes, 2018
Animal communication and motoric behavior develop over time. Often, this temporal dimension has communicative relevance and is organized according to structural patterns.
Ravignani, A.
core   +1 more source

A theoretical framework for estimation of AUCs in complete and incomplete sampling designs. [PDF]

open access: yes, 2009
Nonclinical in vivo animal studies have to be completed before starting clinical studies of the pharmacokinetic behavior of a drug in humans. The drug exposure in animal studies is often measured by the area under the concentration versus time curve (AUC)
Jaki, Thomas, Wolfsegger, Martin J.
core   +1 more source

The apo LETM1 F‐EF‐hand adopts a closed conformation that underlies a multi‐modal sensory role in mitochondria

open access: yesFEBS Letters, EarlyView.
We present the first solution structure of the Ca2+‐depleted LETM1 F‐EF‐hand through a D676A/N678A Ca2+ binding‐deficient mutant, revealing a closed hydrophobic cleft caused by a unique F1‐helix pivot. The apo LETM1 F‐EF‐hand exhibits regiospecific hot and cold unfolding, sensitivity to physiological pH changes and potential for promiscuous heterotypic
Qi‐Tong Lin   +2 more
wiley   +1 more source

AnimalTrack: A Benchmark for Multi-Animal Tracking in the Wild [PDF]

open access: yesarXiv, 2022
Multi-animal tracking (MAT), a multi-object tracking (MOT) problem, is crucial for animal motion and behavior analysis and has many crucial applications such as biology, ecology and animal conservation. Despite its importance, MAT is largely under-explored compared to other MOT problems such as multi-human tracking due to the scarcity of dedicated ...
arxiv  

Chorusing, synchrony, and the evolutionary functions of rhythm

open access: yes, 2014
A central goal of biomusicology is to understand the biological basis of human musicality. One approach to this problem has been to compare core components of human musicality (relative pitch perception, entrainment, etc.) with similar capacities in ...
Bowling, D., Fitch , W., Ravignani, A.
core   +2 more sources

Distinct dysregulated pathways in sporadic and Lynch syndrome‐associated colorectal cancer offer insights for targeted treatment

open access: yesFEBS Letters, EarlyView.
This study explores the distinct molecular mechanisms underlying Lynch syndrome‐associated and sporadic colorectal cancer (CRC). By highlighting the therapeutic potential of targeting the PI3K‐Akt pathway in Lynch syndrome‐associated CRC and the Wnt pathway in sporadic CRC, the findings open avenues for personalised treatment strategies, aiming to ...
May J. Krause   +2 more
wiley   +1 more source

BEEtag: A Low-Cost, Image-Based Tracking System for the Study of Animal Behavior and Locomotion

open access: yesbioRxiv, 2015
A fundamental challenge common to studies of animal movement, behavior, and ecology is the collection of high-quality datasets on spatial positions of animals as they change through space and time.
J. Crall   +3 more
semanticscholar   +1 more source

Immunoregulatory mechanisms of the arachidonic acid pathway in cancer

open access: yesFEBS Letters, EarlyView.
The central role of the arachidonic acid (AA) pathway in anticancer immunity. Enzymes and metabolites of the AA pathway can play both immunosuppressive and immunostimulatory roles in the tumor microenvironment. Therefore, their tailored targeting could be beneficial as a standalone therapy or in combination with current cancer immunotherapy.
Maria Tredicine   +3 more
wiley   +1 more source

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