Results 91 to 100 of about 6,011,412 (305)

I.Q. Zoo The Educated Hen

open access: yes, 1990
A coin deposited into the machine turns on a red light inside the animal chamber which acts as a discriminative stimulus that signals the chicken to pull a rope. Used in Marian Breland Bailey and Keller Breland's I.Q.

core  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Case Study of an Automatic Enrichment Device for Laying Hens on a Free-Range Laying Hen Farm

open access: yesAgriculture, 2019
Access to adequate foraging material can reduce the occurrence of feather pecking and cannibalism in laying hens. Technical devices may help farmers provide enrichment material more effectively. However, research in this field is rare.
Melanie Schmidt   +4 more
doaj   +1 more source

I.Q. Zoo Fortune Telling Chicken

open access: yes, 1990
Machine used in Marian Breland Bailey and Keller Breland's I.Q. Zoo studying operant conditioning. A coin deposited into the machine turns on a red light inside the animal chamber.

core  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

animal2vec and MeerKAT: A self‐supervised transformer for rare‐event raw audio input and a large‐scale reference dataset for bioacoustics

open access: yesMethods in Ecology and Evolution
Bioacoustic research, vital for promoting conservation and understanding animal behaviour and ecology, faces a monumental challenge: analysing vast datasets where animal vocalizations are rare.
Julian C. Schäfer‐Zimmermann   +11 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Female behavior drives the formation of distinct social structures in C57BL/6J versus wild-derived outbred mice in field enclosures

open access: yesBMC Biology
Background Social behavior and social organization have major influences on individual health and fitness. Yet, biomedical research focuses on studying a few genotypes under impoverished social conditions.
Caleb C. Vogt   +10 more
doaj   +1 more source

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