Results 71 to 80 of about 842,571 (263)

Fairly flexible: brown-tufted capuchins and a squirrel monkey adjust their motor responses in a foraging task [PDF]

PeerJ
Prior research on non-human primates has produced contradictory results regarding behavioral flexibility and habit formation. Most observational studies of wild primates show flexibility in foraging behavior, whereas experimental data suggest captive ...
Renee C. Russell, Colleen M. Buckley, Carly B. Rovner, Peter G. Judge   +3 more
doaj   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Experimental validation of in silico predicted RAD locus frequencies using genomic resources and short read data from a model marine mammal

BMC Genomics, 2019
Background Restriction site-associated DNA sequencing (RADseq) has revolutionized the study of wild organisms by allowing cost-effective genotyping of thousands of loci.
David L. J. Vendrami, Jaume Forcada, Joseph I. Hoffman   +2 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

animal2vec and MeerKAT: A self‐supervised transformer for rare‐event raw audio input and a large‐scale reference dataset for bioacoustics

Methods in Ecology and Evolution
Bioacoustic research, vital for promoting conservation and understanding animal behaviour and ecology, faces a monumental challenge: analysing vast datasets where animal vocalizations are rare.
Julian C. Schäfer‐Zimmermann, Vlad Demartsev, Baptiste Averly, Kiran L. Dhanjal‐Adams, Mathieu Duteil, Gabriella Gall, Marius Faiß, Lily Johnson‐Ulrich, Dan Stowell, Marta B. Manser, Marie A. Roch, Ariana Strandburg‐Peshkin   +11 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Case Study of an Automatic Enrichment Device for Laying Hens on a Free-Range Laying Hen Farm

Agriculture, 2019
Access to adequate foraging material can reduce the occurrence of feather pecking and cannibalism in laying hens. Technical devices may help farmers provide enrichment material more effectively. However, research in this field is rare.
Melanie Schmidt, Jenny Stracke, Katja Kulke, Nicole Kemper, Birgit Spindler   +4 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source