Results 71 to 80 of about 6,011,412 (305)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Oilbirds performing non-seasonal intra-tropical migrations reduce flight effort compared to individuals that frequently return to the colony roost

Movement Ecology
Individual behavioural variation is a driver of population dynamics and key for the adaptation and persistence of species. In colonial species, individuals share the same ecological niche and aggregate in space, but they might use different foraging ...
Gustavo Alarcón-Nieto, Adriana A. Maldonado-Chaparro, Carlos Bosque, Franz Kümmeth, Kamran Safi, Martin Wikelski   +5 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Comparative spatial cognition in wild Tanganyikan cichlids: navigation performance varies with home range and shelter availability

Animal Cognition
Spatial cognition varies widely even among closely related species, and identifying the ecological drivers of this variation remains challenging because species typically differ in multiple aspects of their ecology simultaneously.
Zoë Goverts, Maëlan Tomasek, Alex Jordan   +2 more
doaj   +1 more source

Stereotypic Behavior in Fattening Bulls

Animals, 2019
The occurrence of stereotypies in captive animals may indicate restrictions in animal welfare. In cattle, common stereotypies are tongue playing, manipulation of objects, or conspecifics.
Laura Schneider, Nicole Kemper, Birgit Spindler   +2 more
doaj   +1 more source

Chimpanzee Turning Behavior During Spatial Navigation in Virtual Environments [PDF]

Primate spatial navigation is difficult to study in the wild due to limited knowledge of explanatory variables, and in captivity due to limited physical space.
Josep Call, Emma S. McEwen, Janmaat, Karline R. L., Schweller, Kenneth, Call, Josep, Dolins, Francine L., Karline R. L. Janmaat, Sarah E. Koopman, Kenneth Schweller, McEwen, Emma, Allritz, Matthias, Matthias Allritz, Francine L. Dolins, Koopman, Sarah   +13 more
core   +2 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Spray Dried Animal Plasma as an Alternative to Antibiotics in Weanling Pigs [PDF]

, 2010
Piglet health at weaning is compromised due to several stress factors. Following the ban of antibiotic growth promoters new alternatives are required to control these problems. This paper reviews the evidence available for the use of spray dried animal
Torrallardona, David
core