Results 111 to 120 of about 9,348,186 (298)

Experimental validation of in silico predicted RAD locus frequencies using genomic resources and short read data from a model marine mammal

BMC Genomics, 2019
Background Restriction site-associated DNA sequencing (RADseq) has revolutionized the study of wild organisms by allowing cost-effective genotyping of thousands of loci.
David L. J. Vendrami, Jaume Forcada, Joseph I. Hoffman   +2 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Animal Experiments: Conference Report

, 1986
Researchers who use animal subjects and representatives from the Royal Society for the Prevention of Cruelty to Animals and moderate antivivisection groups held a press seminar in London in June 1986.
Dawson, Jane
core  

How Do Perceptions of Zoo Animal Welfare Influence Public Attitudes, Experiences, and Behavioral Intentions? A Mixed-Methods Systematic Review [PDF]

The public expects zoos to provide high standards of animal care. Failing to meet public expectations can have detrimental impacts on public experiences and behavior, which in turn can compromise zoos’ organizational goals relative to conservation and ...
Beth Ventura, Laëtitia Maréchal, Jonathan Cooper, Nicki Phillips   +3 more
core   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

animal2vec and MeerKAT: A self‐supervised transformer for rare‐event raw audio input and a large‐scale reference dataset for bioacoustics

Methods in Ecology and Evolution
Bioacoustic research, vital for promoting conservation and understanding animal behaviour and ecology, faces a monumental challenge: analysing vast datasets where animal vocalizations are rare.
Julian C. Schäfer‐Zimmermann, Vlad Demartsev, Baptiste Averly, Kiran L. Dhanjal‐Adams, Mathieu Duteil, Gabriella Gall, Marius Faiß, Lily Johnson‐Ulrich, Dan Stowell, Marta B. Manser, Marie A. Roch, Ariana Strandburg‐Peshkin   +11 more
doaj   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

FEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia, Anna Dósa, Asha Kiran Maddali, András Jipa, Hajnalka Laczkó‐Dobos, Péter Lőw, Gábor Juhász   +6 more
wiley   +1 more source

Case Study of an Automatic Enrichment Device for Laying Hens on a Free-Range Laying Hen Farm

Agriculture, 2019
Access to adequate foraging material can reduce the occurrence of feather pecking and cannibalism in laying hens. Technical devices may help farmers provide enrichment material more effectively. However, research in this field is rare.
Melanie Schmidt, Jenny Stracke, Katja Kulke, Nicole Kemper, Birgit Spindler   +4 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Plate and Rößler (2024) Video S1

Reactions towards a spider model and a control in three salticid species.Video S1 for: Plate, J., & Rößler, D. C. (2024). Variation in predator recognition across three species of jumping spiders (Salticidae). Animal Behavior and Cognition, 11(1), 50-60.
Animal Behavior & Cognition Journal (12484206)
core   +1 more source