Results 111 to 120 of about 19,581,945 (347)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Preclinical evidence for a novel pharmacotherapeutic approach for treating benzodiazepine addiction

Translational Psychiatry
Benzodiazepines are an important class of psychiatric medicines used widely for the treatment of anxiety and sleep disorders, but clinical use is limited by their significant liability for addiction and physical dependence.
Lais F. Berro, Jemma E. Cook, Eliseu C. Moreira-Junior, Heather L. Hembree, Victoria L. Comfort, Daniela Rüedi-Bettschen, Donna M. Platt, James K. Rowlett   +7 more
doaj   +1 more source

Innovation Onset: A Moderated Mediation Model of High-Involvement Work Practices and Employees’ Innovative Work Behavior

, 2022
Mingxing Li, Hira Salah ud din Khan, Muhammad Salman Chughtai, Thanh Tiep Le   +3 more
openalex   +2 more sources

Characterizing Driving Context from Driver Behavior

, 2017
Because of the increasing availability of spatiotemporal data, a variety of data-analytic applications have become possible. Characterizing driving context, where context may be thought of as a combination of location and time, is a new challenging ...
Craig, R. Bruce, Moosavi, Sobhan, Nandi, Arnab, Omidvar-Tehrani, Behrooz, Ramnath, Rajiv   +4 more
core   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Cue-Evoked Dopamine Release Rapidly Modulates D2 Neurons in the Nucleus Accumbens During Motivated Behavior [PDF]

, 2016
Catarina Owesson-White, Anna M. Belle, Natalie R. Herr, Jessica L. Peele, Preethi Gowrishankar, Regina M. Carelli, R. Mark Wightman   +6 more
openalex   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Facilitatory/inhibitory intracortical imbalance in REM sleep behavior disorder: early electrophysiological marker of neurodegeneration? [PDF]

, 2019
Giuseppe Lanza, Debora Aricò, Bartolo Lanuzza, F. Cosentino, Mariangela Tripodi, Floriana Giardina, Rita Bella, Monica Puligheddu, Giovanni Pennisi, Raffaele Ferri, Manuela Pennisi   +10 more
openalex   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source