Results 121 to 130 of about 16,785,403 (406)

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Linking emotions to behaviors through deep transfer learning [PDF]

open access: yesarXiv, 2019
Human behavior refers to the way humans act and interact. Understanding human behavior is a cornerstone of observational practice, especially in psychotherapy. An important cue of behavior analysis is the dynamical changes of emotions during the conversation.
arxiv  

Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren   +16 more
wiley   +1 more source

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink   +6 more
wiley   +1 more source

How Do Emotions Influence Saving Behavior [PDF]

open access: yes
Employers have moved away from traditional defined benefit pension plans to defined contribution plans such as 401(k)s. As a result, many individuals are now required to make their own retirement saving and investment decisions, which has raised concerns
Deborah J. MacInnis   +2 more
core   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

open access: yesMolecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker   +14 more
wiley   +1 more source

Geometric Singular Perturbation Theory Analysis of an Epidemic Model with Spontaneous Human Behavioral Change [PDF]

open access: yesarXiv, 2020
We consider a model due to Piero Poletti and collaborators that adds spontaneous human behavioral change to the standard SIR epidemic model. In its simplest form, the Poletti model adds one differential equation, motivated by evolutionary game theory, to the SIR model.
arxiv  

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

open access: yesMolecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen   +13 more
wiley   +1 more source

Detecting Unknown Behaviors by Pre-defined Behaviours: An Bayesian Non-parametric Approach [PDF]

open access: yesarXiv, 2019
An automatic mouse behavior recognition system can considerably reduce the workload of experimenters and facilitate the analysis process. Typically, supervised approaches, unsupervised approaches and semi-supervised approaches are applied for behavior recognition purpose under a setting which has all of predefined behaviors.
arxiv  

Designing Environments Conducive to Interpretable Robot Behavior [PDF]

open access: yesarXiv, 2020
Designing robots capable of generating interpretable behavior is a prerequisite for achieving effective human-robot collaboration. This means that the robots need to be capable of generating behavior that aligns with human expectations and, when required, provide explanations to the humans in the loop.
arxiv  

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