Results 171 to 180 of about 13,305,381 (334)
FURTHER STUDIES ON THE BEHAVIOR OF BACTERIA TOWARD GENTIAN VIOLET [PDF]
, 1921 John W. Churchman
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Molecular Oncology, EarlyView.This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci +6 more
wiley +1 more source
Effect of delay interval and cue focality on prospective memory
BMC PsychologyBackground Prospective memory refers to the ability to perform planned things in the appropriate future situations. Due to pointing towards the future, prospective memory usually has a certain amount of time delay. This study investigated the impact of a
Zongbin Sun +5 more
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Studies on Certain Viruses Isolated in the Tropics of Africa and South America: Their Growth and Behavior in the Embryonated Hen Egg [PDF]
, 1952 R. M. Taylor
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Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
THE OCCURRENCE AND HEREDITARY BEHAVIOR OF TWO NEW DOMINANT MUTATIONS IN AN INBRED STRAIN OF DROSOPHILA MELANOGASTER [PDF]
, 1923 Margaret C. Mann
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TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
THE PSYCHIATRIC NURSE AS A BEHAVIORAL ENGINEER1 [PDF]
, 1959 Teodoro Ayllón, Jack Michael
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