Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
An in vitro wear behavior analysis of polymer composite for biomedical application. [PDF]
BioinformationArputham AJ +3 more
europepmc +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
An Exploratory Survey of Latinidad in Behavior Analysis. [PDF]
Behav Anal PractJimenez-Gomez C, Lechago S, Rios D.
europepmc +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Mapping the Evidence on Compassion Skills in Applied Behavior Analysis: Protocol for Scoping Review.
JMIR Res ProtocNunes Longhi Aleixo D +20 more
europepmc +1 more source
The effectiveness of applied behavior analysis program training on enhancing autistic children's emotional-social skills. [PDF]
BMC PsycholDu G, Guo Y, Xu W.
europepmc +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Profiling Generalized Anxiety Disorder on Social Networks: Content and Behavior Analysis.
J Med Internet ResAlhazzaa L, Curcin V.
europepmc +1 more source
Diagnostic behavior analysis of profuse data intrusions in cyber physical systems using adversarial learning techniques. [PDF]
Sci RepSelvarajan S +6 more
europepmc +1 more source