Results 101 to 110 of about 1,763,020 (300)

Study protocol for the Heads-Up trial: a phase II randomized controlled trial investigating head-up tilt sleeping to alleviate orthostatic intolerance in Parkinson’s Disease and parkinsonism

open access: yesBMC Neurology
Background In persons with Parkinson’s Disease (PD) or certain forms of atypical parkinsonism, orthostatic hypotension is common and disabling, yet often underrecognized and undertreated.
Amber H. van der Stam   +9 more
doaj   +1 more source

La especialización del psicopedagogo en la atención a escolares con trastorno de conducta / Training school psychologists to meet the needs of children with behavioral disorders [PDF]

open access: yesTransformación, 2017
The education of students with behavior disorders a challenge for all the countries, teacher improvement and specialization has been an alternative to the Cuban system of education to face it.
Silvia E. Villegas Rodríguez
doaj  

Selective vulnerabilities and biomarkers in neurocognitive aging [version 1; referees: 4 approved]

open access: yesF1000Research, 2017
As the world’s population continues to age, an understanding of the aging brain becomes increasingly crucial. This review focuses on several recent ideas and findings in the study of neurocognitive aging, specifically focusing on episodic memory, and ...
Zachariah Reagh, Michael Yassa
doaj   +1 more source

Assessment of Metabolic Parameters For Autism Spectrum Disorders [PDF]

open access: yes, 2009
Autism is a brain development disorder that first appears during infancy or childhood, and generally follows a steady course without remission. Impairments result from maturation-related changes in various systems of the brain.
Ghosh, S   +4 more
core  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

COMPARING THE RATE OF PREVALNT BEHAVIOUR DISORDERS AMONG ARDEBIL ELEMENTARY SCHOOL STUDENTS WITH AND WITHOUT SPECIFIC LEARNING DISABILITIES [PDF]

open access: yesRavānshināsī-i Afrād-i Istis̠nāyī, 2011
The aim of This study is to investigate the prevalence of behavior disorders among elementary Ardebil school students with and without specific learning disabilties.‏ The subjects of this study were a sample of 377 (191 boys and 186 girls) without ...
Hatam Mohammadi, Ezzat o allah Naderi
doaj  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Sex Differences in Internalizing and Externalizing Behaviors in Children with Autism Spectrum Disorder [PDF]

open access: yes, 2018
This study used a retrospective practice-based research method to compare levels of internalizing and externalizing behaviors of a clinically-ascertained sample of young children with autism spectrum disorder (ASD; n=90).
Cherry, Caroline C
core   +2 more sources

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

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