Results 141 to 150 of about 1,763,020 (300)

Antipsychotics in the Management of Disruptive Behavior Disorders in Children and Adolescents: An Update and Critical Review. [PDF]

Biomedicines, 2022
Rajkumar RP.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Treatment of childhood disruptive behavior disorders and callous-unemotional traits: a systematic review and two multilevel meta-analyses. [PDF]

J Child Psychol Psychiatry, 2023
Perlstein S, Fair M, Hong E, Waller R.
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Contemporary screen time modalities and disruptive behavior disorders in children: a prospective cohort study. [PDF]

J Child Psychol Psychiatry, 2023
Nagata JM, Chu J, Ganson KT, Murray SB, Iyer P, Gabriel KP, Garber AK, Bibbins-Domingo K, Baker FC.   +8 more
europepmc   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Introduction to the Special Issue: Teacher Educators for Children with Behavior Disorders (TECBD) Conference. [PDF]

Educ Treat Children, 2022
Mathur SR, Oakes WP, Clark HG, Common EA.   +3 more
europepmc   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Physical activity and self-esteem: testing direct and indirect relationships associated with psychological and physical mechanisms

Neuropsychiatric Disease and Treatment, 2016
Seyed Hojjat Zamani Sani,1 Zahra Fathirezaie,1 Serge Brand,2 Uwe Pühse,3 Edith Holsboer-Trachsler,2 Markus Gerber,3 Siavash Talepasand4 1Department of Motor Behavior, Faculty of Physical Education and Sport Science, University of Tabriz, Tabriz,
Zamani Sani SH, Fathirezaie Z, Brand S, Pühse U, Holsboer-Trachsler E, Gerber M, Talepasand S   +6 more
doaj  

Alterations in intestinal microbiota and metabolites in individuals with Down syndrome and their correlation with inflammation and behavior disorders in mice. [PDF]

Front Microbiol, 2023
Cai S, Lin J, Li Z, Liu S, Feng Z, Zhang Y, Zhang Y, Huang J, Chen Q.   +8 more
europepmc   +1 more source