Results 11 to 20 of about 1,763,020 (300)

Review about comorbidities of behavioural disorders in children and adolescents: The focus on attention-deficit/hyperactivity disorder [PDF]

open access: yes, 2017
Disruptive behavior disorders (DBD) present high comorbidity rate mainly for opposite-defiant disorders that are frequent among children, adolescents and adults affected by with attention deficit and hyperactivity disorder (ADHD), probably as result of ...
Barbanera F.   +9 more
core   +1 more source

From autism to eating disorders and more: the role of oxytocin in neuropsychiatric disorders [PDF]

open access: yes, 2016
Oxytocin (oxy) is a pituitary neuropeptide hormone synthesized from the paraventricular and supraoptic nuclei within the hypothalamus. Like other neuropeptides, oxy can modulate a wide range of neurotransmitter and neuromodulator activities. Additionally,
Di Bonaventura, Maria Vittoria Micioni   +3 more
core   +2 more sources

Synergistic effects of amyloid-beta and wild-type human tau on dendritic spine loss in a floxed double transgenic model of Alzheimer's disease

open access: yesNeurobiology of Disease, 2014
Synapse number is the best indicator of cognitive impairment In Alzheimer's disease (AD), yet the respective contributions of Aβ and tau, particularly human wild-type tau, to synapse loss remain undefined.
Meredith A. Chabrier   +4 more
doaj   +1 more source

A Trem2 R47H mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaques

open access: yesMolecular Neurodegeneration, 2023
Background The TREM2 R47H variant is one of the strongest genetic risk factors for late-onset Alzheimer’s Disease (AD). Unfortunately, many current Trem2 R47H mouse models are associated with cryptic mRNA splicing of the mutant allele that produces a ...
Kristine M. Tran   +28 more
doaj   +1 more source

The Meaning of Spiritual Life and the Reduction of Behavioral Disorders for Youth Members of the English Study Club (ESC)

open access: yesEDUCATIO: Journal of Education, 2021
Solving the problem of behavior disorders in adolescents can be done by encouraging the emergence of the meaning of spiritual life. The strategy is carried out by exploring the meaning of life through learning the Koran, praying in congregation and ...
Eka Sri Wahyuni
doaj   +1 more source

Protocol for single-nucleus ATAC sequencing and bioinformatic analysis in frozen human brain tissue

open access: yesSTAR Protocols, 2022
Summary: Single-nucleus ATAC sequencing (snATAC-seq) employs a hyperactive Tn5 transposase to gain precise information about the cis-regulatory elements in specific cell types. However, the standard protocol of snATAC-seq is not optimized for all tissues,
Zechuan Shi   +4 more
doaj   +1 more source

Complete recovery from anxiety disorders following Cognitive Behavioural Therapy in children and adolescents: a meta analysis [PDF]

open access: yes, 2017
Cognitive Behavior Therapy (CBT) is a well-established treatment for childhood anxiety disorders. Meta-analyses have concluded that approximately 60% of children recover following treatment, however these include studies using a broad range of diagnostic
Cooper, Peter   +6 more
core   +1 more source

Association study of suicidal behavior and affective disorders with a genetic polymorphism in ABCG1, a positional candidate on chromosome 21q22.3 [PDF]

open access: yes, 2000
The gene that codes for the ABC transporter ABCG1 is located in a chromosomal susceptibility region (21q22.3) for affective disorders. Genetic variations in ABCG1 have been associated with affective disorders in Japanese males.
Anghelescu, I.   +9 more
core   +1 more source

The Nicotinic Acetylcholine Receptor as a Target for Antidepressant Drug Development

open access: yesThe Scientific World Journal, 2012
An important new area of antidepressant drug development involves targeting the nicotinic acetylcholine receptor (nAChR). This receptor, which is distributed widely in regions of the brain associated with depression, is also implicated in other important
Noah S. Philip   +3 more
doaj   +1 more source

Pathological Skin Picking: Case Presentation and Review of the Literature [PDF]

open access: yes, 2015
Pathological skin picking is a condition in which patients induce skin lesions through repetitive, compulsive excoriations of normal skin or skin with minor surface irregularities and they admit their role in the production of the lesions, but are unable
Benea, Vasile   +5 more
core   +3 more sources

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