Review about comorbidities of behavioural disorders in children and adolescents: The focus on attention-deficit/hyperactivity disorder [PDF]
Disruptive behavior disorders (DBD) present high comorbidity rate mainly for opposite-defiant disorders that are frequent among children, adolescents and adults affected by with attention deficit and hyperactivity disorder (ADHD), probably as result of ...
Barbanera F. +9 more
core +1 more source
From autism to eating disorders and more: the role of oxytocin in neuropsychiatric disorders [PDF]
Oxytocin (oxy) is a pituitary neuropeptide hormone synthesized from the paraventricular and supraoptic nuclei within the hypothalamus. Like other neuropeptides, oxy can modulate a wide range of neurotransmitter and neuromodulator activities. Additionally,
Di Bonaventura, Maria Vittoria Micioni +3 more
core +2 more sources
Synapse number is the best indicator of cognitive impairment In Alzheimer's disease (AD), yet the respective contributions of Aβ and tau, particularly human wild-type tau, to synapse loss remain undefined.
Meredith A. Chabrier +4 more
doaj +1 more source
Background The TREM2 R47H variant is one of the strongest genetic risk factors for late-onset Alzheimer’s Disease (AD). Unfortunately, many current Trem2 R47H mouse models are associated with cryptic mRNA splicing of the mutant allele that produces a ...
Kristine M. Tran +28 more
doaj +1 more source
Solving the problem of behavior disorders in adolescents can be done by encouraging the emergence of the meaning of spiritual life. The strategy is carried out by exploring the meaning of life through learning the Koran, praying in congregation and ...
Eka Sri Wahyuni
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Protocol for single-nucleus ATAC sequencing and bioinformatic analysis in frozen human brain tissue
Summary: Single-nucleus ATAC sequencing (snATAC-seq) employs a hyperactive Tn5 transposase to gain precise information about the cis-regulatory elements in specific cell types. However, the standard protocol of snATAC-seq is not optimized for all tissues,
Zechuan Shi +4 more
doaj +1 more source
Complete recovery from anxiety disorders following Cognitive Behavioural Therapy in children and adolescents: a meta analysis [PDF]
Cognitive Behavior Therapy (CBT) is a well-established treatment for childhood anxiety disorders. Meta-analyses have concluded that approximately 60% of children recover following treatment, however these include studies using a broad range of diagnostic
Cooper, Peter +6 more
core +1 more source
Association study of suicidal behavior and affective disorders with a genetic polymorphism in ABCG1, a positional candidate on chromosome 21q22.3 [PDF]
The gene that codes for the ABC transporter ABCG1 is located in a chromosomal susceptibility region (21q22.3) for affective disorders. Genetic variations in ABCG1 have been associated with affective disorders in Japanese males.
Anghelescu, I. +9 more
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The Nicotinic Acetylcholine Receptor as a Target for Antidepressant Drug Development
An important new area of antidepressant drug development involves targeting the nicotinic acetylcholine receptor (nAChR). This receptor, which is distributed widely in regions of the brain associated with depression, is also implicated in other important
Noah S. Philip +3 more
doaj +1 more source
Pathological Skin Picking: Case Presentation and Review of the Literature [PDF]
Pathological skin picking is a condition in which patients induce skin lesions through repetitive, compulsive excoriations of normal skin or skin with minor surface irregularities and they admit their role in the production of the lesions, but are unable
Benea, Vasile +5 more
core +3 more sources

